Design, synthesis, and biological evaluation of tetrahydroquinolinones and tetrahydroquinolines with anticancer activity

Design, synthesis, and biological evaluation of tetrahydroquinolinones and tetrahydroquinolines with anticancer activity

Abstract Colorectal cancer (CRC) is the most commonly diagnosed cancer in Europe and the United States and the second leading cause of cancer related mortality. A therapeutic strategy used for the treatment of CRC involves targeting the intracellular levels of reactive oxygen species (ROS). In this...

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Bibliographic Details
Main Authors:	Małgorzata Ryczkowska, Natalia Maciejewska, Mateusz Olszewski, Milena Witkowska, Sławomir Makowiec
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-06-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-022-13867-x

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