Effect of Pro-Kinetic Drugs on Post –Prandial Glycaemic Surge in Type 2 Diabetic Patients
Background: To study the effects of pro-kinetic agents on post-prandial glycaemia in type 2 diabetes mellitus. Methods :In this comparative study one hundred and eighty patients with Type 2 diabetes mellitus and features of gastroparesis were randomly recruited. They were divided randomly into two g...
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| Format: | Article |
| Language: | English |
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Rawalpindi Medical University
2012-12-01
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| Series: | Journal of Rawalpindi Medical College |
| Subjects: | |
| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/558 |
| _version_ | 1818806176469483520 |
|---|---|
| author | Asim Zulfiqar |
| author_facet | Asim Zulfiqar |
| author_sort | Asim Zulfiqar |
| collection | DOAJ |
| description | Background: To study the effects of pro-kinetic
agents on post-prandial glycaemia in type 2 diabetes
mellitus.
Methods :In this comparative study one hundred
and eighty patients with Type 2 diabetes mellitus
and features of gastroparesis were randomly
recruited. They were divided randomly into two
groups of ninety each.Group I was given oral antidiabetic
agents and placebo. Group II was given
oral anti-diabetic agents along with domperidone.
Mean levels of glycaemic difference. Difference
between Premeal and two hours postmeal and
glycaemic levels were determined and compared in
the two groups.
Results :Mean fasting blood sugar of Group I was
168.57 mg/dl and 2 hours postprandial was 296.73
mg/dl. In Group II mean fasting blood sugar was
201.24 mg/dl and mean 2 hours postprandial blood
sugar was 296.42 mg/dl. Mean difference in fasting
and 2 hours post prandial was 156.38 mg/dl and
114.15 mg/dl, respectively in Group I and II.
Conclusion: Mean difference between fasting and
2 hours postprandial blood sugar is significantly low
in patients taking prokinetic drugs, as compared to
the diabetics not taking pro-kinetic drugs. |
| first_indexed | 2024-12-18T19:05:37Z |
| format | Article |
| id | doaj.art-fb290043fdd54bcea5ad7778facf3f99 |
| institution | Directory Open Access Journal |
| issn | 1683-3562 1683-3570 |
| language | English |
| last_indexed | 2024-12-18T19:05:37Z |
| publishDate | 2012-12-01 |
| publisher | Rawalpindi Medical University |
| record_format | Article |
| series | Journal of Rawalpindi Medical College |
| spelling | doaj.art-fb290043fdd54bcea5ad7778facf3f992022-12-21T20:56:27ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702012-12-01162Effect of Pro-Kinetic Drugs on Post –Prandial Glycaemic Surge in Type 2 Diabetic PatientsAsim Zulfiqar0*Department of Medicine Islamic International Medical College and Railway Hospital, RawalpindiBackground: To study the effects of pro-kinetic agents on post-prandial glycaemia in type 2 diabetes mellitus. Methods :In this comparative study one hundred and eighty patients with Type 2 diabetes mellitus and features of gastroparesis were randomly recruited. They were divided randomly into two groups of ninety each.Group I was given oral antidiabetic agents and placebo. Group II was given oral anti-diabetic agents along with domperidone. Mean levels of glycaemic difference. Difference between Premeal and two hours postmeal and glycaemic levels were determined and compared in the two groups. Results :Mean fasting blood sugar of Group I was 168.57 mg/dl and 2 hours postprandial was 296.73 mg/dl. In Group II mean fasting blood sugar was 201.24 mg/dl and mean 2 hours postprandial blood sugar was 296.42 mg/dl. Mean difference in fasting and 2 hours post prandial was 156.38 mg/dl and 114.15 mg/dl, respectively in Group I and II. Conclusion: Mean difference between fasting and 2 hours postprandial blood sugar is significantly low in patients taking prokinetic drugs, as compared to the diabetics not taking pro-kinetic drugs.https://www.journalrmc.com/index.php/JRMC/article/view/558ncretinGlucagon like Peptide |
| spellingShingle | Asim Zulfiqar Effect of Pro-Kinetic Drugs on Post –Prandial Glycaemic Surge in Type 2 Diabetic Patients Journal of Rawalpindi Medical College ncretin Glucagon like Peptide |
| title | Effect of Pro-Kinetic Drugs on Post –Prandial Glycaemic Surge in Type 2 Diabetic Patients |
| title_full | Effect of Pro-Kinetic Drugs on Post –Prandial Glycaemic Surge in Type 2 Diabetic Patients |
| title_fullStr | Effect of Pro-Kinetic Drugs on Post –Prandial Glycaemic Surge in Type 2 Diabetic Patients |
| title_full_unstemmed | Effect of Pro-Kinetic Drugs on Post –Prandial Glycaemic Surge in Type 2 Diabetic Patients |
| title_short | Effect of Pro-Kinetic Drugs on Post –Prandial Glycaemic Surge in Type 2 Diabetic Patients |
| title_sort | effect of pro kinetic drugs on post prandial glycaemic surge in type 2 diabetic patients |
| topic | ncretin Glucagon like Peptide |
| url | https://www.journalrmc.com/index.php/JRMC/article/view/558 |
| work_keys_str_mv | AT asimzulfiqar effectofprokineticdrugsonpostprandialglycaemicsurgeintype2diabeticpatients |