Down-regulation of cyclin D2 in amyloid β toxicity, inflammation, and Alzheimer’s disease

Down-regulation of cyclin D2 in amyloid β toxicity, inflammation, and Alzheimer’s disease

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In the current study, we analyzed the effects of the systemic inflammatory response (SIR) and amyloid β (Aβ) peptide on the expression of genes encoding cyclins and cyclin-dependent kinase (Cdk) in: (i) PC12 cells overexpressing human beta amyloid precursor protein (βAPP), wild-type (APPwt-PC12), or...

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Bibliographic Details
Main Authors: Grzegorz A. Czapski, Magdalena Cieślik, Emilia Białopiotrowicz, Walter J. Lukiw, Joanna B. Strosznajder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601534/?tool=EBI

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