Iron status determined changes in health measures induced by nordic walking with time-restricted eating in older adults– a randomised trial
Abstract Background and aims This study evaluated whether stored iron determines the adaptive response induced by Nordic walking (NW) training combined with 10 hours’ time-restricted eating (TRE) in older adults. Trial design and methods Twenty-four participants underwent 12-week NW training support...
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | BMC Geriatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12877-024-04876-8 |
| _version_ | 1797233294384824320 |
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| author | Jakub Antoni Kortas Joanna Reczkowicz Ulana Juhas Ewa Ziemann Aleksandra Świątczak Katarzyna Prusik Szczepan Olszewski Nakisa Soltani Ewa Rodziewicz-Flis Damian Flis Małgorzata Żychowska Grażyna Gałęzowska Jędrzej Antosiewicz |
| author_facet | Jakub Antoni Kortas Joanna Reczkowicz Ulana Juhas Ewa Ziemann Aleksandra Świątczak Katarzyna Prusik Szczepan Olszewski Nakisa Soltani Ewa Rodziewicz-Flis Damian Flis Małgorzata Żychowska Grażyna Gałęzowska Jędrzej Antosiewicz |
| author_sort | Jakub Antoni Kortas |
| collection | DOAJ |
| description | Abstract Background and aims This study evaluated whether stored iron determines the adaptive response induced by Nordic walking (NW) training combined with 10 hours’ time-restricted eating (TRE) in older adults. Trial design and methods Twenty-four participants underwent 12-week NW training supported by 10 h of TRE. The group was divided due to baseline ferritin concentration low < 75 ng/ml (LF) and high level ≥ 75 ng/ml (HF). Body composition, physical fitness and blood collection were assessed at baseline and post-intervention. Results NW + TRE induced a statistically significant decrease in ferritin levels in all participants (p = 0.01). Additionally, statistically significant intergroup differences in the LF vs. HF in the reduction of serum ferritin levels (p = 0.04) were observed. The procedure NW + TRE diminished HbA1c levels (p < 0.01) and glucose in all participants (p = 0.05). The range of HbA1c drop was more pronounced among those participants who experienced a greater decrease in the stored iron (p = 0.04, $$ {\eta }_{p}^{2}$$ =0.17, F=4.59). Greater changes in body weight and percent of body fat were recorded in the HF group (for both p<0.01). Conclusion Body iron stores determine the effects of a 12-week NW + TRE intervention on serum ferritin. The changes in HbA1c are more pronounced in subjects with a higher decrease in serum ferritin. Trial registration All experimental protocols were approved by the Bioethical Committee of the Regional Medical Society in Gdansk, Poland (NKBBN/330/2021) according to the Declaration of Helsinki. We confirm that all methods were carried out in accordance with relevant guidelines and regulations. The trial was registered as a clinical trial (NCT05229835, date of first registration: 14/01/2022, direct link: https://classic.clinicaltrials.gov/ct2/show/NCT05229835 ). Informed consent was obtained from all subjects. |
| first_indexed | 2024-04-24T16:13:53Z |
| format | Article |
| id | doaj.art-fb2cb7c1b6d44db89f457d5dd2736a5e |
| institution | Directory Open Access Journal |
| issn | 1471-2318 |
| language | English |
| last_indexed | 2024-04-24T16:13:53Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj.art-fb2cb7c1b6d44db89f457d5dd2736a5e2024-03-31T11:34:29ZengBMCBMC Geriatrics1471-23182024-03-0124111110.1186/s12877-024-04876-8Iron status determined changes in health measures induced by nordic walking with time-restricted eating in older adults– a randomised trialJakub Antoni Kortas0Joanna Reczkowicz1Ulana Juhas2Ewa Ziemann3Aleksandra Świątczak4Katarzyna Prusik5Szczepan Olszewski6Nakisa Soltani7Ewa Rodziewicz-Flis8Damian Flis9Małgorzata Żychowska10Grażyna Gałęzowska11Jędrzej Antosiewicz12Department of Health and Natural Sciences, Gdansk University of Physical Education and SportDepartment of Bioenergetics and Physiology of Exercise, Medical University of GdanskDepartment of Bioenergetics and Physiology of Exercise, Medical University of GdanskDepartment of Athletics, Strength and Conditioning, Poznan University of Physical EducationDepartment of Medical Biology and Genetics, Faculty of Biology, University of GdanskFaculty of Tourism and Recreation, Department of Health Promotion, Gdansk University of Physical Education and SportDepartment of Bioenergetics and Physiology of Exercise, Medical University of GdanskDepartment of Bioenergetics and Physiology of Exercise, Medical University of GdanskDepartment of Physiotherapy, Gdansk University of Physical Education and SportDepartment of Pharmaceutical Pathophysiology, Faculty of Pharmacy, Medical University of GdanskDepartment of Sport, Faculty of Physical Education, Kazimierz Wielki University in BydgoszczDepartment of Bioenergetics and Physiology of Exercise, Medical University of GdanskDepartment of Bioenergetics and Physiology of Exercise, Medical University of GdanskAbstract Background and aims This study evaluated whether stored iron determines the adaptive response induced by Nordic walking (NW) training combined with 10 hours’ time-restricted eating (TRE) in older adults. Trial design and methods Twenty-four participants underwent 12-week NW training supported by 10 h of TRE. The group was divided due to baseline ferritin concentration low < 75 ng/ml (LF) and high level ≥ 75 ng/ml (HF). Body composition, physical fitness and blood collection were assessed at baseline and post-intervention. Results NW + TRE induced a statistically significant decrease in ferritin levels in all participants (p = 0.01). Additionally, statistically significant intergroup differences in the LF vs. HF in the reduction of serum ferritin levels (p = 0.04) were observed. The procedure NW + TRE diminished HbA1c levels (p < 0.01) and glucose in all participants (p = 0.05). The range of HbA1c drop was more pronounced among those participants who experienced a greater decrease in the stored iron (p = 0.04, $$ {\eta }_{p}^{2}$$ =0.17, F=4.59). Greater changes in body weight and percent of body fat were recorded in the HF group (for both p<0.01). Conclusion Body iron stores determine the effects of a 12-week NW + TRE intervention on serum ferritin. The changes in HbA1c are more pronounced in subjects with a higher decrease in serum ferritin. Trial registration All experimental protocols were approved by the Bioethical Committee of the Regional Medical Society in Gdansk, Poland (NKBBN/330/2021) according to the Declaration of Helsinki. We confirm that all methods were carried out in accordance with relevant guidelines and regulations. The trial was registered as a clinical trial (NCT05229835, date of first registration: 14/01/2022, direct link: https://classic.clinicaltrials.gov/ct2/show/NCT05229835 ). Informed consent was obtained from all subjects.https://doi.org/10.1186/s12877-024-04876-8FerritinHbA1cSoluble transferrin receptorBody ironSerum glucose |
| spellingShingle | Jakub Antoni Kortas Joanna Reczkowicz Ulana Juhas Ewa Ziemann Aleksandra Świątczak Katarzyna Prusik Szczepan Olszewski Nakisa Soltani Ewa Rodziewicz-Flis Damian Flis Małgorzata Żychowska Grażyna Gałęzowska Jędrzej Antosiewicz Iron status determined changes in health measures induced by nordic walking with time-restricted eating in older adults– a randomised trial BMC Geriatrics Ferritin HbA1c Soluble transferrin receptor Body iron Serum glucose |
| title | Iron status determined changes in health measures induced by nordic walking with time-restricted eating in older adults– a randomised trial |
| title_full | Iron status determined changes in health measures induced by nordic walking with time-restricted eating in older adults– a randomised trial |
| title_fullStr | Iron status determined changes in health measures induced by nordic walking with time-restricted eating in older adults– a randomised trial |
| title_full_unstemmed | Iron status determined changes in health measures induced by nordic walking with time-restricted eating in older adults– a randomised trial |
| title_short | Iron status determined changes in health measures induced by nordic walking with time-restricted eating in older adults– a randomised trial |
| title_sort | iron status determined changes in health measures induced by nordic walking with time restricted eating in older adults a randomised trial |
| topic | Ferritin HbA1c Soluble transferrin receptor Body iron Serum glucose |
| url | https://doi.org/10.1186/s12877-024-04876-8 |
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