Modes of Action of 1,8-Cineol in Infections and Inflammation

The monoterpene 1,8-Cineol is a natural plant-based therapeutic agent that is commonly applied to treat different inflammatory diseases due to its mucolytic, anti-microbial and anti-inflammatory properties. It has become increasingly clear in the recent years that 1,8-Cineol spreads almost everywher...

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Bibliographic Details
Main Authors: Ralph Pries, Stephanie Jeschke, Anke Leichtle, Karl-Ludwig Bruchhage
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/13/6/751
Description
Summary:The monoterpene 1,8-Cineol is a natural plant-based therapeutic agent that is commonly applied to treat different inflammatory diseases due to its mucolytic, anti-microbial and anti-inflammatory properties. It has become increasingly clear in the recent years that 1,8-Cineol spreads almost everywhere in the human body after its oral administration, from the gut to the blood to the brain. Its anti-microbial potential and even its anti-viral effects have been observed to include numerous bacteria and fungi species. Many recent studies help to better understand the cellular and molecular immunological consequences of 1,8-Cineol treatment in inflammatory diseases and further provide information concerning the mechanistic modes of action in the regulation of distinct inflammatory biosynthetic pathways. This review aims to present a holistic and understandable overview of the different aspects of 1,8-Cineol in infections and inflammation.
ISSN:2218-1989