Permanent impairment of birth and survival of cortical and hippocampal proliferating cells following excessive drinking during alcohol dependence

Permanent impairment of birth and survival of cortical and hippocampal proliferating cells following excessive drinking during alcohol dependence

Experimenter-delivered alcohol decreases adult hippocampal neurogenesis and hippocampal-dependent learning and memory. The present study used clinically relevant rodent models of nondependent limited access alcohol self-administration and excessive drinking during alcohol dependence (alcohol self-ad...

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Bibliographic Details
Main Authors: Heather N. Richardson, Stephanie H. Chan, Elena F. Crawford, Youn Kyung Lee, Cindy K. Funk, George F. Koob, Chitra D. Mandyam
Format: Article
Language:English
Published: Elsevier 2009-10-01
Series:Neurobiology of Disease
Subjects:
Prefrontal cortex
Subgranular zone
Self-administration
Alcohol vapor
Ki-67
Bromodeoxyuridine
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109001247

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