Evaluation of the Rapid Sepsityper protocol and specific MBT-Sepsityper module for the identification of bacteremia and fungemia using Bruker Biotyper MALDI-TOF MS

The rapid identification method, the Rapid Sepsityper protocol with a specific MBT-Sepsityper module (Bruker Daltonics), based on the MALDI Biotyper platform, accurately identified 93.5% (116/124) of microorganisms at the species level in the 124 flagged blood culture samples from patients with mono...

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Bibliographic Details
Main Authors: Hsiu-Hsien Lin, Kun-Hao Tseng, Ni Tien, Yu-Tzu Lin, Jiaxin Yu, Po-Ren Hsueh, Der-Yang Cho
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Microbiology, Immunology and Infection
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Online Access:http://www.sciencedirect.com/science/article/pii/S1684118222001037
Description
Summary:The rapid identification method, the Rapid Sepsityper protocol with a specific MBT-Sepsityper module (Bruker Daltonics), based on the MALDI Biotyper platform, accurately identified 93.5% (116/124) of microorganisms at the species level in the 124 flagged blood culture samples from patients with monomicrobial bloodstream infections. Gram-negative bacilli (95.6%, 43/45) had a higher identification rate than Gram-positive cocci (93.3%, 70/75) and yeasts (75%, 3/4). The Rapid Sepsityper protocol displayed poor identification performance for polymicrobial samples.
ISSN:1684-1182