EXPERIMENTAL TESTING OF AN IN VIVO METHOD OF PHOTOTOXICITY EVALUATION

EXPERIMENTAL TESTING OF AN IN VIVO METHOD OF PHOTOTOXICITY EVALUATION

At present all new medicinal products and cosmetics that absorb medium-wavelength UVB, long-wavelength UVA, or visible light in the range 290–700 nm need to be tested for potential phototoxicity. phototoxicity is evaluated by both in vitro and in vivo methods. There are guidelines for in vitro photo...

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Bibliographic Details
Main Authors: V. А. Vavilova, E. V. Shekunova, V. A. Kashkin, M. N. Makarova, V. G. Makarov, A. Ya. Khaymenov
Format: Article
Language:Russian
Published: Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2018-06-01
Series:Регуляторные исследования и экспертиза лекарственных средств
Subjects:
phototoxicity
phototoxic reactions
uv radiation
tetracycline
ketorolac
outbred rats
Online Access:https://www.vedomostincesmp.ru/jour/article/view/182

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