Characterization and Comparison of the Divergent Metabolic Consequences of High-Sugar and High-Fat Diets in Male Wistar Rats

Characterization and Comparison of the Divergent Metabolic Consequences of High-Sugar and High-Fat Diets in Male Wistar Rats

Diet-induced obesity (DIO) in laboratory rodents can serve as a model with which to study the pathophysiology of obesity, but obesogenic diets (high-sugar and/or high-fat) are often poorly characterised and simplistically aimed at inducing metabolic derangements for the purpose of testing the therap...

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Bibliographic Details
Main Authors: Liske Kotzé-Hörstmann, Annibale Cois, Rabia Johnson, Lawrence Mabasa, Samukelisiwe Shabalala, Paul J. Van Jaarsveld, Hanél Sadie-Van Gijsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Physiology
Subjects:
obesity
rodent models
obesogenic diets
dietary intervention studies
metabolic fingerprinting
multivariate analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.904366/full

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