Effects of rumen bypass melatonin feeding (RBMF) on milk quality and mastitis of Holstein cows
Cow mastitis is a major problem frequently encountered by dairy farmers and it is manifested by the high number of somatic cells and the low quality of the milk. The conventional treatment for mastitis is use of antibiotics. In the current study, a new approach is applied to target this disorder: ru...
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| Format: | Article |
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PeerJ Inc.
2020-05-01
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| Series: | PeerJ |
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| Online Access: | https://peerj.com/articles/9147.pdf |
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| author | Songyang Yao Hao Wu Hui Ma Yao Fu Wenjuan Wei Tiankun Wang Shengyu Guan Hai Yang Xiubo Li Jiangpeng Guo Yongqiang Lu Lu Zhang Changwang He Yi Chang Guoshi Liu |
| author_facet | Songyang Yao Hao Wu Hui Ma Yao Fu Wenjuan Wei Tiankun Wang Shengyu Guan Hai Yang Xiubo Li Jiangpeng Guo Yongqiang Lu Lu Zhang Changwang He Yi Chang Guoshi Liu |
| author_sort | Songyang Yao |
| collection | DOAJ |
| description | Cow mastitis is a major problem frequently encountered by dairy farmers and it is manifested by the high number of somatic cells and the low quality of the milk. The conventional treatment for mastitis is use of antibiotics. In the current study, a new approach is applied to target this disorder: rumen bypass melatonin feeding (RBMF). The RBMF significantly reduced milk somatic cell count and improved milk nutritional values with the elevated protein, fat and dry matter levels. This approach also suppresses the stress and proinflammatory responses of the cows indicated by the reduced serum cortisol, TNF-α and IL-6 and increased IL-10 levels. Importantly, the beneficial effects of RBMF have lasted for several days after termination of the treatment. The effects of melatonin on the mastitis are probably attributed to the antioxidant and anti-inflammatory activities of melatonin. Considering the none or low toxicity of melatonin to organisms and the no invasive nature of this approach, we recommend that RBMF could be used in large scale in the dairy farming to target the cow mastitis. |
| first_indexed | 2024-03-09T06:43:55Z |
| format | Article |
| id | doaj.art-fb3a5a6ab0564dfea7020744fa61dbbf |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T06:43:55Z |
| publishDate | 2020-05-01 |
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| record_format | Article |
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| spelling | doaj.art-fb3a5a6ab0564dfea7020744fa61dbbf2023-12-03T10:42:42ZengPeerJ Inc.PeerJ2167-83592020-05-018e914710.7717/peerj.9147Effects of rumen bypass melatonin feeding (RBMF) on milk quality and mastitis of Holstein cowsSongyang Yao0Hao Wu1Hui Ma2Yao Fu3Wenjuan Wei4Tiankun Wang5Shengyu Guan6Hai Yang7Xiubo Li8Jiangpeng Guo9Yongqiang Lu10Lu Zhang11Changwang He12Yi Chang13Guoshi Liu14Beijing Key Laboratory of Animal Genetic Improvement, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, ChinaBeijing Key Laboratory of Animal Genetic Improvement, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, ChinaBeijing Shounong Animal Husbandry Development Co. LTD, Beijing, ChinaBeijing Key Laboratory of Animal Genetic Improvement, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, ChinaBeijing Shounong Animal Husbandry Development Co. LTD, Beijing, ChinaBeijing Changping District Animal Disease Prevention and Control Center, Beijing, ChinaBeijing Key Laboratory of Animal Genetic Improvement, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, ChinaBeijing Key Laboratory of Animal Genetic Improvement, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, ChinaChinese Academy of Agricultural Sciences Feed Research Institute, Beijing, ChinaBeijing Animal Husbandry Station, Beijing, ChinaBeijing Animal Husbandry Station, Beijing, ChinaBeijing Key Laboratory of Animal Genetic Improvement, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, ChinaBeijing Shounong Animal Husbandry Development Co. LTD, Beijing, ChinaBeijing Shounong Animal Husbandry Development Co. LTD, Beijing, ChinaBeijing Key Laboratory of Animal Genetic Improvement, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, ChinaCow mastitis is a major problem frequently encountered by dairy farmers and it is manifested by the high number of somatic cells and the low quality of the milk. The conventional treatment for mastitis is use of antibiotics. In the current study, a new approach is applied to target this disorder: rumen bypass melatonin feeding (RBMF). The RBMF significantly reduced milk somatic cell count and improved milk nutritional values with the elevated protein, fat and dry matter levels. This approach also suppresses the stress and proinflammatory responses of the cows indicated by the reduced serum cortisol, TNF-α and IL-6 and increased IL-10 levels. Importantly, the beneficial effects of RBMF have lasted for several days after termination of the treatment. The effects of melatonin on the mastitis are probably attributed to the antioxidant and anti-inflammatory activities of melatonin. Considering the none or low toxicity of melatonin to organisms and the no invasive nature of this approach, we recommend that RBMF could be used in large scale in the dairy farming to target the cow mastitis.https://peerj.com/articles/9147.pdfMelatoninMastitisInflammationMilk quality |
| spellingShingle | Songyang Yao Hao Wu Hui Ma Yao Fu Wenjuan Wei Tiankun Wang Shengyu Guan Hai Yang Xiubo Li Jiangpeng Guo Yongqiang Lu Lu Zhang Changwang He Yi Chang Guoshi Liu Effects of rumen bypass melatonin feeding (RBMF) on milk quality and mastitis of Holstein cows PeerJ Melatonin Mastitis Inflammation Milk quality |
| title | Effects of rumen bypass melatonin feeding (RBMF) on milk quality and mastitis of Holstein cows |
| title_full | Effects of rumen bypass melatonin feeding (RBMF) on milk quality and mastitis of Holstein cows |
| title_fullStr | Effects of rumen bypass melatonin feeding (RBMF) on milk quality and mastitis of Holstein cows |
| title_full_unstemmed | Effects of rumen bypass melatonin feeding (RBMF) on milk quality and mastitis of Holstein cows |
| title_short | Effects of rumen bypass melatonin feeding (RBMF) on milk quality and mastitis of Holstein cows |
| title_sort | effects of rumen bypass melatonin feeding rbmf on milk quality and mastitis of holstein cows |
| topic | Melatonin Mastitis Inflammation Milk quality |
| url | https://peerj.com/articles/9147.pdf |
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