EXTRACRANIAL METASTASIS OF GLIOBLASTOMA: A RARE CASE

Glioblastoma is the most common primary malignant tumor in the neural tissue and a highly aggressive primary tumor in human. It involves glial cells in 52% of functional brain tissue cases and 20% of all intracranial tumors. Extra cranial metastasis of Glioblastoma is very rare. Metastasis outside C...

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Main Authors: Dessika Rahmawati, Eko Arisetijono Marhaendraputro, Shahdevi Nandar Kurniawan, Andina Wirathmawati
Format: Article
Language:English
Published: University of Brawijaya 2019-01-01
Series:Malang Neurology Journal
Subjects:
Online Access:http://mnj.ub.ac.id/index.php/mnj/article/view/389
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author Dessika Rahmawati
Eko Arisetijono Marhaendraputro
Shahdevi Nandar Kurniawan
Andina Wirathmawati
author_facet Dessika Rahmawati
Eko Arisetijono Marhaendraputro
Shahdevi Nandar Kurniawan
Andina Wirathmawati
author_sort Dessika Rahmawati
collection DOAJ
description Glioblastoma is the most common primary malignant tumor in the neural tissue and a highly aggressive primary tumor in human. It involves glial cells in 52% of functional brain tissue cases and 20% of all intracranial tumors. Extra cranial metastasis of Glioblastoma is very rare. Metastasis outside CNS was uncommon in GBM but it could occur with frequency 0.2% and can spread in head and neck sites. The mechanism of this spread is not understood yet. The extracranial spread routes were speculated on the direct lymphatic connections, the venous system and the adjacent structure like dura and bone. We present a case of female patient with a known glioblastoma who had an extracranial metastasis on her left neck with complete Radiotherapy n Chemotherapy and survive more than 2 years.
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spelling doaj.art-fb3c74befb024f31867d9ac83c2457182022-12-21T18:59:59ZengUniversity of BrawijayaMalang Neurology Journal2407-67242442-50012019-01-0151515410.21776/ub.mnj.2019.005.01.1088EXTRACRANIAL METASTASIS OF GLIOBLASTOMA: A RARE CASEDessika Rahmawati0Eko Arisetijono Marhaendraputro1Shahdevi Nandar Kurniawan2Andina Wirathmawati3Neurology Department, Faculty of Medicine, Universitas BrawijayaDepartment of Neurology Faculty of Medicine Brawijaya University, MalangDepartment of Neurology Faculty of Medicine Brawijaya University, MalangDepartment of Neurology Faculty of Medicine Brawijaya University, MalangGlioblastoma is the most common primary malignant tumor in the neural tissue and a highly aggressive primary tumor in human. It involves glial cells in 52% of functional brain tissue cases and 20% of all intracranial tumors. Extra cranial metastasis of Glioblastoma is very rare. Metastasis outside CNS was uncommon in GBM but it could occur with frequency 0.2% and can spread in head and neck sites. The mechanism of this spread is not understood yet. The extracranial spread routes were speculated on the direct lymphatic connections, the venous system and the adjacent structure like dura and bone. We present a case of female patient with a known glioblastoma who had an extracranial metastasis on her left neck with complete Radiotherapy n Chemotherapy and survive more than 2 years.http://mnj.ub.ac.id/index.php/mnj/article/view/389Glioblastoma, Extracranial metastasis, Neck mass, Rare case
spellingShingle Dessika Rahmawati
Eko Arisetijono Marhaendraputro
Shahdevi Nandar Kurniawan
Andina Wirathmawati
EXTRACRANIAL METASTASIS OF GLIOBLASTOMA: A RARE CASE
Malang Neurology Journal
Glioblastoma, Extracranial metastasis, Neck mass, Rare case
title EXTRACRANIAL METASTASIS OF GLIOBLASTOMA: A RARE CASE
title_full EXTRACRANIAL METASTASIS OF GLIOBLASTOMA: A RARE CASE
title_fullStr EXTRACRANIAL METASTASIS OF GLIOBLASTOMA: A RARE CASE
title_full_unstemmed EXTRACRANIAL METASTASIS OF GLIOBLASTOMA: A RARE CASE
title_short EXTRACRANIAL METASTASIS OF GLIOBLASTOMA: A RARE CASE
title_sort extracranial metastasis of glioblastoma a rare case
topic Glioblastoma, Extracranial metastasis, Neck mass, Rare case
url http://mnj.ub.ac.id/index.php/mnj/article/view/389
work_keys_str_mv AT dessikarahmawati extracranialmetastasisofglioblastomaararecase
AT ekoarisetijonomarhaendraputro extracranialmetastasisofglioblastomaararecase
AT shahdevinandarkurniawan extracranialmetastasisofglioblastomaararecase
AT andinawirathmawati extracranialmetastasisofglioblastomaararecase