Analysis Dosage of Boron in BNCT with Simulation Method Using PHITS (Particle and Heavy Ion Transport Code System) Program

Abstrak – Cancer is a dangerous disease which is one of the main causes of death in the world, which is 8.8 million deaths in 2015. A new method has been developed for the treatment of cancer with small side effects, Boron Neutron Capture Therapy (BNCT). BNCT is based on the ability of non-radioacti...

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Main Authors: Laura Laudensia Senly Jalut, Ni Nyoman Rupiasih, Yohanes Sardjono
Format: Article
Language:English
Published: Universitas Udayana 2020-02-01
Series:Buletin Fisika
Online Access:https://ojs.unud.ac.id/index.php/buletinfisika/article/view/47572
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author Laura Laudensia Senly Jalut
Ni Nyoman Rupiasih
Yohanes Sardjono
author_facet Laura Laudensia Senly Jalut
Ni Nyoman Rupiasih
Yohanes Sardjono
author_sort Laura Laudensia Senly Jalut
collection DOAJ
description Abstrak – Cancer is a dangerous disease which is one of the main causes of death in the world, which is 8.8 million deaths in 2015. A new method has been developed for the treatment of cancer with small side effects, Boron Neutron Capture Therapy (BNCT). BNCT is based on the ability of non-radioactive isotopes Boron-10 to capture thermal neutrons. Boron is the main key of the BNCT process wherein, radiation of cancer cells can be carried out selectively if the cancer contains high concentrations of boron. Boron doses in cancer cells cannot be measured directly, therefore artificial network methods are used to compute doses computationally, namely the Monte Carlo method with the Particle and Heavy Ion Transport Code System (PHITS) program. Boron dose used was 10, 20 and 30 ?g/g. It was found that the greater the boron dose the greater the number of neutrons absorbed. The results showed that the largest absorption dose occurred in the Gross Tumor Volume (GTV) area of ??7.7076E-10 Gy/cm2. Key words: Cancer, BNCT, Dose of Boron, PHITS.
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spelling doaj.art-fb3cc69ac7454d02b5595e25365446fc2023-02-26T01:41:40ZengUniversitas UdayanaBuletin Fisika1411-46902580-97332020-02-012111747572Analysis Dosage of Boron in BNCT with Simulation Method Using PHITS (Particle and Heavy Ion Transport Code System) ProgramLaura Laudensia Senly Jalut0Ni Nyoman Rupiasih1Yohanes Sardjono2Fisika Universitas UdayanaUdayana UniversityPSTA BATANAbstrak – Cancer is a dangerous disease which is one of the main causes of death in the world, which is 8.8 million deaths in 2015. A new method has been developed for the treatment of cancer with small side effects, Boron Neutron Capture Therapy (BNCT). BNCT is based on the ability of non-radioactive isotopes Boron-10 to capture thermal neutrons. Boron is the main key of the BNCT process wherein, radiation of cancer cells can be carried out selectively if the cancer contains high concentrations of boron. Boron doses in cancer cells cannot be measured directly, therefore artificial network methods are used to compute doses computationally, namely the Monte Carlo method with the Particle and Heavy Ion Transport Code System (PHITS) program. Boron dose used was 10, 20 and 30 ?g/g. It was found that the greater the boron dose the greater the number of neutrons absorbed. The results showed that the largest absorption dose occurred in the Gross Tumor Volume (GTV) area of ??7.7076E-10 Gy/cm2. Key words: Cancer, BNCT, Dose of Boron, PHITS.https://ojs.unud.ac.id/index.php/buletinfisika/article/view/47572
spellingShingle Laura Laudensia Senly Jalut
Ni Nyoman Rupiasih
Yohanes Sardjono
Analysis Dosage of Boron in BNCT with Simulation Method Using PHITS (Particle and Heavy Ion Transport Code System) Program
Buletin Fisika
title Analysis Dosage of Boron in BNCT with Simulation Method Using PHITS (Particle and Heavy Ion Transport Code System) Program
title_full Analysis Dosage of Boron in BNCT with Simulation Method Using PHITS (Particle and Heavy Ion Transport Code System) Program
title_fullStr Analysis Dosage of Boron in BNCT with Simulation Method Using PHITS (Particle and Heavy Ion Transport Code System) Program
title_full_unstemmed Analysis Dosage of Boron in BNCT with Simulation Method Using PHITS (Particle and Heavy Ion Transport Code System) Program
title_short Analysis Dosage of Boron in BNCT with Simulation Method Using PHITS (Particle and Heavy Ion Transport Code System) Program
title_sort analysis dosage of boron in bnct with simulation method using phits particle and heavy ion transport code system program
url https://ojs.unud.ac.id/index.php/buletinfisika/article/view/47572
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AT ninyomanrupiasih analysisdosageofboroninbnctwithsimulationmethodusingphitsparticleandheavyiontransportcodesystemprogram
AT yohanessardjono analysisdosageofboroninbnctwithsimulationmethodusingphitsparticleandheavyiontransportcodesystemprogram