Prolonged diarrhea among under-five children in Bangladesh: Burden and risk factors.
<h4>Introduction & background</h4>Prolonged (duration >7 to 13 days) diarrhea (ProD) in under-five children is a universal health problem including Bangladesh. Data on epidemiology and associated or risk factors of ProD are limited, particularly in Bangladesh where a high burden o...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0273148 |
| _version_ | 1811181952297861120 |
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| author | Md Iqbal Hossain A S G Faruque Monira Sarmin Mohammod Jobayer Chisti Tahmeed Ahmed |
| author_facet | Md Iqbal Hossain A S G Faruque Monira Sarmin Mohammod Jobayer Chisti Tahmeed Ahmed |
| author_sort | Md Iqbal Hossain |
| collection | DOAJ |
| description | <h4>Introduction & background</h4>Prolonged (duration >7 to 13 days) diarrhea (ProD) in under-five children is a universal health problem including Bangladesh. Data on epidemiology and associated or risk factors of ProD are limited, particularly in Bangladesh where a high burden of ProD is reported. This study intended to assess the case load of ProD and its associated or risk factors compared to acute diarrhea (AD, duration ≤7 days).<h4>Methods</h4>We analyzed the data collected between 1996-2014 from a hospital-based Diarrheal-Disease-Surveillance-System (DDSS) in the 'Dhaka Hospital' of International Centre for Diarrhoeal Diseases, Bangladesh (icddr,b). The DDSS enrolled a 2% systematic sample, regardless of age, sex, and diarrhea severity. The data included information on socio-demographic factors, environmental history, clinical characteristics, nutritional status, and diarrhea-pathogens. After cleaning of data, relevant information of 21,566 under-five children were available who reported with ≤13 days diarrhea (including AD and ProD), and their data were analyzed. Variables found significantly associated with ProD compared to AD in bi-variate analysis were used in logistic regression model after checking the multicollinearity between independent variables.<h4>Results</h4>The mean±SD age of the children was 14.9±11.7 months and 40.4% were female; 7.6% had ProD and 92.4% had AD. Age <12 months, mucoid- or bloody-stool, warmer months (April-September), drug used at home before seeking care from hospital, and history of diarrhea within last one month were found associated with ProD (p<0.05); however, rotavirus infection was less common in children with ProD (p<0.05). ProD children more often needed inpatient admission than AD children (14.4 vs. 6.3, p<0.001). Case fatality rate of ProD vs. AD was 0.3% (n = 5) vs. 0.1% (n- = 22) respectively (p = 0.051).<h4>Conclusion</h4>A considerable proportion (7.6%) of under-five children reporting to icddr,b hospital suffered from ProD. Understanding the above-mentioned associated or risk factors is likely to help policy makers formulating appropriate strategies for alleviating the burden and effectively managing ProD in under-five children. |
| first_indexed | 2024-04-11T09:25:18Z |
| format | Article |
| id | doaj.art-fb4493ea138b49569493e5bff748d3b2 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-11T09:25:18Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
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| series | PLoS ONE |
| spelling | doaj.art-fb4493ea138b49569493e5bff748d3b22022-12-22T04:32:03ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-011710e027314810.1371/journal.pone.0273148Prolonged diarrhea among under-five children in Bangladesh: Burden and risk factors.Md Iqbal HossainA S G FaruqueMonira SarminMohammod Jobayer ChistiTahmeed Ahmed<h4>Introduction & background</h4>Prolonged (duration >7 to 13 days) diarrhea (ProD) in under-five children is a universal health problem including Bangladesh. Data on epidemiology and associated or risk factors of ProD are limited, particularly in Bangladesh where a high burden of ProD is reported. This study intended to assess the case load of ProD and its associated or risk factors compared to acute diarrhea (AD, duration ≤7 days).<h4>Methods</h4>We analyzed the data collected between 1996-2014 from a hospital-based Diarrheal-Disease-Surveillance-System (DDSS) in the 'Dhaka Hospital' of International Centre for Diarrhoeal Diseases, Bangladesh (icddr,b). The DDSS enrolled a 2% systematic sample, regardless of age, sex, and diarrhea severity. The data included information on socio-demographic factors, environmental history, clinical characteristics, nutritional status, and diarrhea-pathogens. After cleaning of data, relevant information of 21,566 under-five children were available who reported with ≤13 days diarrhea (including AD and ProD), and their data were analyzed. Variables found significantly associated with ProD compared to AD in bi-variate analysis were used in logistic regression model after checking the multicollinearity between independent variables.<h4>Results</h4>The mean±SD age of the children was 14.9±11.7 months and 40.4% were female; 7.6% had ProD and 92.4% had AD. Age <12 months, mucoid- or bloody-stool, warmer months (April-September), drug used at home before seeking care from hospital, and history of diarrhea within last one month were found associated with ProD (p<0.05); however, rotavirus infection was less common in children with ProD (p<0.05). ProD children more often needed inpatient admission than AD children (14.4 vs. 6.3, p<0.001). Case fatality rate of ProD vs. AD was 0.3% (n = 5) vs. 0.1% (n- = 22) respectively (p = 0.051).<h4>Conclusion</h4>A considerable proportion (7.6%) of under-five children reporting to icddr,b hospital suffered from ProD. Understanding the above-mentioned associated or risk factors is likely to help policy makers formulating appropriate strategies for alleviating the burden and effectively managing ProD in under-five children.https://doi.org/10.1371/journal.pone.0273148 |
| spellingShingle | Md Iqbal Hossain A S G Faruque Monira Sarmin Mohammod Jobayer Chisti Tahmeed Ahmed Prolonged diarrhea among under-five children in Bangladesh: Burden and risk factors. PLoS ONE |
| title | Prolonged diarrhea among under-five children in Bangladesh: Burden and risk factors. |
| title_full | Prolonged diarrhea among under-five children in Bangladesh: Burden and risk factors. |
| title_fullStr | Prolonged diarrhea among under-five children in Bangladesh: Burden and risk factors. |
| title_full_unstemmed | Prolonged diarrhea among under-five children in Bangladesh: Burden and risk factors. |
| title_short | Prolonged diarrhea among under-five children in Bangladesh: Burden and risk factors. |
| title_sort | prolonged diarrhea among under five children in bangladesh burden and risk factors |
| url | https://doi.org/10.1371/journal.pone.0273148 |
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