Sex differences in fiber connection from the striatum to subcortical and cortical regions

The striatum is an important subcortical structure with extensive connections to other regions of the brain. These connections are believed to play important roles in behaviors such as reward-related processes and impulse control, which show significant sex differences. However, little is known abou...

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Main Authors: XUEMEI LEI, Zhuo Han, Chuansheng Chen, Lu Bai, Gui Xue, Qi Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Computational Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncom.2016.00100/full
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author XUEMEI LEI
Zhuo Han
Chuansheng Chen
Lu Bai
Gui Xue
Qi Dong
author_facet XUEMEI LEI
Zhuo Han
Chuansheng Chen
Lu Bai
Gui Xue
Qi Dong
author_sort XUEMEI LEI
collection DOAJ
description The striatum is an important subcortical structure with extensive connections to other regions of the brain. These connections are believed to play important roles in behaviors such as reward-related processes and impulse control, which show significant sex differences. However, little is known about sex differences in the striatum-projected fiber connectivity. The current study examined sex differences between 50 Chinese males and 79 Chinese females in their fiber connections between the striatum and nine selected cortical and subcortical regions. Despite overall similarities, males showed stronger fiber connections between the left caudate and rostral cingulate cortex, between the right putamen and the lateral orbitofrontal cortex, between the bilateral putamen and the ventro-lateral prefrontal cortex, and between the right caudate and the ventro-lateral prefrontal cortex, whereas females showed stronger fiber connections between the right putamen and the dorsolateral prefrontal cortex, between bilateral caudate and hippocampus, and between the left putamen and hippocampus. These findings help us to understand sex differences in the striatum-projected fiber connections and their implications for sex differences in behaviors.
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spelling doaj.art-fb451351afde46d3bafa3cc49ce21dd42022-12-21T23:15:19ZengFrontiers Media S.A.Frontiers in Computational Neuroscience1662-51882016-09-011010.3389/fncom.2016.00100206851Sex differences in fiber connection from the striatum to subcortical and cortical regionsXUEMEI LEI0Zhuo Han1Chuansheng Chen2Lu Bai3Gui Xue4Qi Dong5Beijing Normal UniversityBeijing Normal UniversityUniversity of California, IrvineBeijing Normal UniversityBeijing Normal UniversityBeijing Normal UniversityThe striatum is an important subcortical structure with extensive connections to other regions of the brain. These connections are believed to play important roles in behaviors such as reward-related processes and impulse control, which show significant sex differences. However, little is known about sex differences in the striatum-projected fiber connectivity. The current study examined sex differences between 50 Chinese males and 79 Chinese females in their fiber connections between the striatum and nine selected cortical and subcortical regions. Despite overall similarities, males showed stronger fiber connections between the left caudate and rostral cingulate cortex, between the right putamen and the lateral orbitofrontal cortex, between the bilateral putamen and the ventro-lateral prefrontal cortex, and between the right caudate and the ventro-lateral prefrontal cortex, whereas females showed stronger fiber connections between the right putamen and the dorsolateral prefrontal cortex, between bilateral caudate and hippocampus, and between the left putamen and hippocampus. These findings help us to understand sex differences in the striatum-projected fiber connections and their implications for sex differences in behaviors.http://journal.frontiersin.org/Journal/10.3389/fncom.2016.00100/fullDiffusion Tensor ImagingPutamensex differenceStriatumCaudateFiber connection
spellingShingle XUEMEI LEI
Zhuo Han
Chuansheng Chen
Lu Bai
Gui Xue
Qi Dong
Sex differences in fiber connection from the striatum to subcortical and cortical regions
Frontiers in Computational Neuroscience
Diffusion Tensor Imaging
Putamen
sex difference
Striatum
Caudate
Fiber connection
title Sex differences in fiber connection from the striatum to subcortical and cortical regions
title_full Sex differences in fiber connection from the striatum to subcortical and cortical regions
title_fullStr Sex differences in fiber connection from the striatum to subcortical and cortical regions
title_full_unstemmed Sex differences in fiber connection from the striatum to subcortical and cortical regions
title_short Sex differences in fiber connection from the striatum to subcortical and cortical regions
title_sort sex differences in fiber connection from the striatum to subcortical and cortical regions
topic Diffusion Tensor Imaging
Putamen
sex difference
Striatum
Caudate
Fiber connection
url http://journal.frontiersin.org/Journal/10.3389/fncom.2016.00100/full
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AT lubai sexdifferencesinfiberconnectionfromthestriatumtosubcorticalandcorticalregions
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