The effects of androgen deprivation on working memory and quality of life in prostate cancer patients: The roles of hypothalamic connectivity

The effects of androgen deprivation on working memory and quality of life in prostate cancer patients: The roles of hypothalamic connectivity

Abstract Background Androgen deprivation therapy (ADT) has been associated with adverse effects on the brain. ADT alters testosterone levels via its action on the hypothalamus‐pituitary‐gonadal axis and may influence hypothalamic functions. Given the wide regional connectivity of the hypothalamus an...

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Bibliographic Details
Main Authors: Shefali Chaudhary, Simon Zhornitsky, Alicia Roy, Christine Summers, Tim Ahles, Chiang‐Shan R. Li, Herta H. Chao
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Cancer Medicine
Subjects:
androgen deprivation therapy
cognition
hypothalamus
prostate cancer
quality of life
resting state fMRI
Online Access:https://doi.org/10.1002/cam4.4704

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