Anatomical and visual outcomes of fovea-sparing internal limiting membrane peeling with or without inverted flap technique for myopic foveoschisis
Abstract Background Vitrectomy and peeling of the internal limiting membrane (ILM) was an effective therapeutic approach for myopic foveoschisis with progressive visual loss. This study investigated the anatomical and visual outcomes of fovea-sparing ILM peeling with or without the inverted flap tec...
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-022-02679-2 |
| _version_ | 1797801545996173312 |
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| author | Dezhi Zheng Zijing Huang Qin Zeng Yifan Wang Shirong Chen Jingsheng Yi Danqi Fang Dingguo Huang Weiqi Chen |
| author_facet | Dezhi Zheng Zijing Huang Qin Zeng Yifan Wang Shirong Chen Jingsheng Yi Danqi Fang Dingguo Huang Weiqi Chen |
| author_sort | Dezhi Zheng |
| collection | DOAJ |
| description | Abstract Background Vitrectomy and peeling of the internal limiting membrane (ILM) was an effective therapeutic approach for myopic foveoschisis with progressive visual loss. This study investigated the anatomical and visual outcomes of fovea-sparing ILM peeling with or without the inverted flap technique for patients with symptomatic myopic foveoschisis (MF). Methods We retrospectively reviewed the clinical data of patients with MF. Vitrectomy with fovea-sparing ILM peeling and air tamponade was performed in all patients. The primary outcome measures included best-corrected visual acuity (BCVA), mean macular thickness (MMT), and central foveal thickness (CFT). Depending on whether an inverted ILM flap technique was utilized, further subgroup comparisons between the inverted flap group and the non-inverted flap group were conducted. Results Twenty-six eyes of 22 patients were included. Fifteen eyes were underwent fovea-sparing ILM peeling without inverted ILM flap and 11 of the 26 eyes were treated with fovea-sparing ILM peeling and an inverted ILM flap technique. In the mean follow-up period of 10.74 ± 4.58 months, a significant improvement in BCVA was observed from 0.97 ± 0.45 logMAR to 0.58 ± 0.51 logMAR (P < 0.01), during which the BCVA of 20 eyes (76.92%) improved and remained stable in 5 eyes (19.23%). Moreover, a positive correlation was also found between the preoperative BCVA and the postoperative BCVA (r = 0.50, P = 0.01). At the last visit, the final MMT decreased from 492.69 ± 209.62 μm to 234.73 ± 86.09 μm, and the CFT reduced from 296.08 ± 209.22 μm to 138.31 ± 73.92 μm (all P < 0.01). A subgroup analysis found no significant differences in BCVA, MMT, or CFT between the inverted and non-inverted flap groups (all P > 0.05). Conclusion Fovea-sparing ILM peeling with or without inverted flap technique resulted in favorable visual and anatomical outcomes for the treatment of MF. An important factor affecting the postoperative visual outcome was the preoperative visual acuity. Our study found no significant difference between the presence and absence of the inverted ILM flap. |
| first_indexed | 2024-03-13T04:52:07Z |
| format | Article |
| id | doaj.art-fb4572dd453549c2aac99fa04e7f4116 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-03-13T04:52:07Z |
| publishDate | 2022-11-01 |
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| series | BMC Ophthalmology |
| spelling | doaj.art-fb4572dd453549c2aac99fa04e7f41162023-06-18T11:09:44ZengBMCBMC Ophthalmology1471-24152022-11-012211810.1186/s12886-022-02679-2Anatomical and visual outcomes of fovea-sparing internal limiting membrane peeling with or without inverted flap technique for myopic foveoschisisDezhi Zheng0Zijing Huang1Qin Zeng2Yifan Wang3Shirong Chen4Jingsheng Yi5Danqi Fang6Dingguo Huang7Weiqi Chen8Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong KongJoint Shantou International Eye Center of Shantou University and the Chinese University of Hong KongJoint Shantou International Eye Center of Shantou University and the Chinese University of Hong KongJoint Shantou International Eye Center of Shantou University and the Chinese University of Hong KongJoint Shantou International Eye Center of Shantou University and the Chinese University of Hong KongJoint Shantou International Eye Center of Shantou University and the Chinese University of Hong KongJoint Shantou International Eye Center of Shantou University and the Chinese University of Hong KongJoint Shantou International Eye Center of Shantou University and the Chinese University of Hong KongJoint Shantou International Eye Center of Shantou University and the Chinese University of Hong KongAbstract Background Vitrectomy and peeling of the internal limiting membrane (ILM) was an effective therapeutic approach for myopic foveoschisis with progressive visual loss. This study investigated the anatomical and visual outcomes of fovea-sparing ILM peeling with or without the inverted flap technique for patients with symptomatic myopic foveoschisis (MF). Methods We retrospectively reviewed the clinical data of patients with MF. Vitrectomy with fovea-sparing ILM peeling and air tamponade was performed in all patients. The primary outcome measures included best-corrected visual acuity (BCVA), mean macular thickness (MMT), and central foveal thickness (CFT). Depending on whether an inverted ILM flap technique was utilized, further subgroup comparisons between the inverted flap group and the non-inverted flap group were conducted. Results Twenty-six eyes of 22 patients were included. Fifteen eyes were underwent fovea-sparing ILM peeling without inverted ILM flap and 11 of the 26 eyes were treated with fovea-sparing ILM peeling and an inverted ILM flap technique. In the mean follow-up period of 10.74 ± 4.58 months, a significant improvement in BCVA was observed from 0.97 ± 0.45 logMAR to 0.58 ± 0.51 logMAR (P < 0.01), during which the BCVA of 20 eyes (76.92%) improved and remained stable in 5 eyes (19.23%). Moreover, a positive correlation was also found between the preoperative BCVA and the postoperative BCVA (r = 0.50, P = 0.01). At the last visit, the final MMT decreased from 492.69 ± 209.62 μm to 234.73 ± 86.09 μm, and the CFT reduced from 296.08 ± 209.22 μm to 138.31 ± 73.92 μm (all P < 0.01). A subgroup analysis found no significant differences in BCVA, MMT, or CFT between the inverted and non-inverted flap groups (all P > 0.05). Conclusion Fovea-sparing ILM peeling with or without inverted flap technique resulted in favorable visual and anatomical outcomes for the treatment of MF. An important factor affecting the postoperative visual outcome was the preoperative visual acuity. Our study found no significant difference between the presence and absence of the inverted ILM flap.https://doi.org/10.1186/s12886-022-02679-2Myopic foveoschisisVitrectomyFovea-sparingInternal limiting membrane |
| spellingShingle | Dezhi Zheng Zijing Huang Qin Zeng Yifan Wang Shirong Chen Jingsheng Yi Danqi Fang Dingguo Huang Weiqi Chen Anatomical and visual outcomes of fovea-sparing internal limiting membrane peeling with or without inverted flap technique for myopic foveoschisis BMC Ophthalmology Myopic foveoschisis Vitrectomy Fovea-sparing Internal limiting membrane |
| title | Anatomical and visual outcomes of fovea-sparing internal limiting membrane peeling with or without inverted flap technique for myopic foveoschisis |
| title_full | Anatomical and visual outcomes of fovea-sparing internal limiting membrane peeling with or without inverted flap technique for myopic foveoschisis |
| title_fullStr | Anatomical and visual outcomes of fovea-sparing internal limiting membrane peeling with or without inverted flap technique for myopic foveoschisis |
| title_full_unstemmed | Anatomical and visual outcomes of fovea-sparing internal limiting membrane peeling with or without inverted flap technique for myopic foveoschisis |
| title_short | Anatomical and visual outcomes of fovea-sparing internal limiting membrane peeling with or without inverted flap technique for myopic foveoschisis |
| title_sort | anatomical and visual outcomes of fovea sparing internal limiting membrane peeling with or without inverted flap technique for myopic foveoschisis |
| topic | Myopic foveoschisis Vitrectomy Fovea-sparing Internal limiting membrane |
| url | https://doi.org/10.1186/s12886-022-02679-2 |
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