Single-cell analysis reveals novel clonally expanded monocytes associated with IL1β–IL1R2 pair in acute inflammatory demyelinating polyneuropathy

Single-cell analysis reveals novel clonally expanded monocytes associated with IL1β–IL1R2 pair in acute inflammatory demyelinating polyneuropathy

Abstract Guillain–Barré syndrome (GBS) is an autoimmune disorder wherein the composition and gene expression patterns of peripheral blood immune cells change significantly. It is triggered by antigens with similar epitopes to Schwann cells that stimulate a maladaptive immune response against periphe...

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Bibliographic Details
Main Authors: Meng Li, Jihe Song, Pengqi Yin, Hongping Chen, Yingju Wang, Chen Xu, Fangchao Jiang, Haining Wang, Baichao Han, Xinshu Du, Wei Wang, Guozhong Li, Di Zhong
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32427-5

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https://doi.org/10.1038/s41598-023-32427-5

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