| Summary: | Background. Senile asthenia is characterized by a decrease in the function and
reserve of the physiological systems of the body, including the cardiovascular system. Senile
asthenia is considered as a process of accelerated aging with a cumulative manifestation
of age-related disorders in many physiological systems that predispose to adverse outcomes.
Cardiovascular pathology is one of the main comorbidities observed in COVID-19.
The aim of the study is to assess the prevalence of cardiovascular diseases in patients with
senile asthenia syndrome against the background of a new coronavirus infection. Materials
and methods. The study included 54 patients who were hospitalized at the covid hospital in
Penza. In the course of the study, laboratory and instrumental indicators were analyzed. All
patients underwent assessment of SA using the index of senile asthenia. Results. When analyzing
the data obtained when calculating the index of senile asthenia, 61.1% (n=33) of patients
suffered from SA. Among concomitant comorbid conditions, arterial hypertension
was detected in 78.8%, dyslipidemia was 54.5%, diabetes mellitus in 21.2%, atrial fibrillation
in 12.1% of patients. Heart failure with reduced ejection fraction (LV EF <40%) was
detected in 4 patients (17.4%), intermediate ejection fraction (LV EF 40-50%) in 6 patients
(26%), preserved ejection fraction (LV EF > 50%) determined in 13 patients (56.5%). Ischemic
heart disease in this category of patients occurred in 10.4% of cases. Conclusions.
Major cardiovascular and metabolic comorbidities such as hypertension, coronary heart
disease, atrial fibrillation, and diabetes mellitus contribute to a poor prognosis in patients
with frailty due to COVID-19. All patients require careful hemodynamic and electrocardiographic
monitoring.
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