<i>Hibiscus sabdariffa</i> in Diabetes Prevention and Treatment—Does It Work? An Evidence-Based Review

Diabetes is currently a global health problem that is already reported as an epidemic. This metabolic disease, characterized by a disturbance in the carbohydrate, protein, and lipid metabolism, is often accompanied by disorders of several organs. Its treatment is expensive and often difficult to con...

Full description

Bibliographic Details
Main Authors: Daniel Jamrozik, Weronika Borymska, Ilona Kaczmarczyk-Żebrowska
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/11/14/2134
_version_ 1827597140771209216
author Daniel Jamrozik
Weronika Borymska
Ilona Kaczmarczyk-Żebrowska
author_facet Daniel Jamrozik
Weronika Borymska
Ilona Kaczmarczyk-Żebrowska
author_sort Daniel Jamrozik
collection DOAJ
description Diabetes is currently a global health problem that is already reported as an epidemic. This metabolic disease, characterized by a disturbance in the carbohydrate, protein, and lipid metabolism, is often accompanied by disorders of several organs. Its treatment is expensive and often difficult to control. Therefore, it seems necessary to search for new drugs and solutions to facilitate therapy and reduce treatment costs. Herbal medicines are becoming more and more popular. <i>Hibiscus sabdariffa</i> (roselle) is a plant that grows wild in a tropical climate. It has been used in folk medicine for thousands of years. Thanks to the numerous active compounds, including polyphenols, polysaccharides, organic acids, or pectins, it is reported to exhibit hypoglycemic, antioxidant, hypotensive, and anti-lipidemic activities and numerous indirect effects that are related to them. The aim of this review was to update the knowledge about the therapeutic effects of roselle in diabetes and its comorbidities based on in vitro, animal, and human studies. After a careful analysis of the scientific literature, it can be stated that roselle is a promising product that can be used either on its own or as an addition to the conventional treatment regimens to prevent or treat diabetes and its accompanying diseases.
first_indexed 2024-03-09T03:25:02Z
format Article
id doaj.art-fb4a925c7a574b10aa89bfc5663d178f
institution Directory Open Access Journal
issn 2304-8158
language English
last_indexed 2024-03-09T03:25:02Z
publishDate 2022-07-01
publisher MDPI AG
record_format Article
series Foods
spelling doaj.art-fb4a925c7a574b10aa89bfc5663d178f2023-12-03T15:03:46ZengMDPI AGFoods2304-81582022-07-011114213410.3390/foods11142134<i>Hibiscus sabdariffa</i> in Diabetes Prevention and Treatment—Does It Work? An Evidence-Based ReviewDaniel Jamrozik0Weronika Borymska1Ilona Kaczmarczyk-Żebrowska2Department of Pharmacognosy and Phytochemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Katowice, Jagiellońska 4, 41-200 Sosnowiec, PolandDepartment of Pharmacognosy and Phytochemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Katowice, Jagiellońska 4, 41-200 Sosnowiec, PolandDepartment of Pharmacognosy and Phytochemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Katowice, Jagiellońska 4, 41-200 Sosnowiec, PolandDiabetes is currently a global health problem that is already reported as an epidemic. This metabolic disease, characterized by a disturbance in the carbohydrate, protein, and lipid metabolism, is often accompanied by disorders of several organs. Its treatment is expensive and often difficult to control. Therefore, it seems necessary to search for new drugs and solutions to facilitate therapy and reduce treatment costs. Herbal medicines are becoming more and more popular. <i>Hibiscus sabdariffa</i> (roselle) is a plant that grows wild in a tropical climate. It has been used in folk medicine for thousands of years. Thanks to the numerous active compounds, including polyphenols, polysaccharides, organic acids, or pectins, it is reported to exhibit hypoglycemic, antioxidant, hypotensive, and anti-lipidemic activities and numerous indirect effects that are related to them. The aim of this review was to update the knowledge about the therapeutic effects of roselle in diabetes and its comorbidities based on in vitro, animal, and human studies. After a careful analysis of the scientific literature, it can be stated that roselle is a promising product that can be used either on its own or as an addition to the conventional treatment regimens to prevent or treat diabetes and its accompanying diseases.https://www.mdpi.com/2304-8158/11/14/2134diabetes<i>Hibiscus sabdariffa</i>extractshypoglycemicantioxidantantilipidemic
spellingShingle Daniel Jamrozik
Weronika Borymska
Ilona Kaczmarczyk-Żebrowska
<i>Hibiscus sabdariffa</i> in Diabetes Prevention and Treatment—Does It Work? An Evidence-Based Review
Foods
diabetes
<i>Hibiscus sabdariffa</i>
extracts
hypoglycemic
antioxidant
antilipidemic
title <i>Hibiscus sabdariffa</i> in Diabetes Prevention and Treatment—Does It Work? An Evidence-Based Review
title_full <i>Hibiscus sabdariffa</i> in Diabetes Prevention and Treatment—Does It Work? An Evidence-Based Review
title_fullStr <i>Hibiscus sabdariffa</i> in Diabetes Prevention and Treatment—Does It Work? An Evidence-Based Review
title_full_unstemmed <i>Hibiscus sabdariffa</i> in Diabetes Prevention and Treatment—Does It Work? An Evidence-Based Review
title_short <i>Hibiscus sabdariffa</i> in Diabetes Prevention and Treatment—Does It Work? An Evidence-Based Review
title_sort i hibiscus sabdariffa i in diabetes prevention and treatment does it work an evidence based review
topic diabetes
<i>Hibiscus sabdariffa</i>
extracts
hypoglycemic
antioxidant
antilipidemic
url https://www.mdpi.com/2304-8158/11/14/2134
work_keys_str_mv AT danieljamrozik ihibiscussabdariffaiindiabetespreventionandtreatmentdoesitworkanevidencebasedreview
AT weronikaborymska ihibiscussabdariffaiindiabetespreventionandtreatmentdoesitworkanevidencebasedreview
AT ilonakaczmarczykzebrowska ihibiscussabdariffaiindiabetespreventionandtreatmentdoesitworkanevidencebasedreview