Potential Cancer- and Alzheimer’s Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual Screening

Bibliographic Details
Main Authors: Mark Tristan Quimque, Kin Israel Notarte, Arianne Letada, Rey Arturo Fernandez, Delfin Yñigo Pilapil, Kirstin Rhys Pueblos, Jay Carl Agbay, Hans-Martin Dahse, Arlette Wenzel-Storjohann, Deniz Tasdemir, Abbas Khan, Dong-Qing Wei, Allan Patrick Gose Macabeo
Format: Article
Language:English
Published: American Chemical Society 2021-03-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.1c00137
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author Mark Tristan Quimque
Kin Israel Notarte
Arianne Letada
Rey Arturo Fernandez
Delfin Yñigo Pilapil
Kirstin Rhys Pueblos
Jay Carl Agbay
Hans-Martin Dahse
Arlette Wenzel-Storjohann
Deniz Tasdemir
Abbas Khan
Dong-Qing Wei
Allan Patrick Gose Macabeo
author_facet Mark Tristan Quimque
Kin Israel Notarte
Arianne Letada
Rey Arturo Fernandez
Delfin Yñigo Pilapil
Kirstin Rhys Pueblos
Jay Carl Agbay
Hans-Martin Dahse
Arlette Wenzel-Storjohann
Deniz Tasdemir
Abbas Khan
Dong-Qing Wei
Allan Patrick Gose Macabeo
author_sort Mark Tristan Quimque
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spelling doaj.art-fb4e83ae93914db59599fadeb98f53912022-12-21T18:03:54ZengAmerican Chemical SocietyACS Omega2470-13432021-03-016128403841710.1021/acsomega.1c00137Potential Cancer- and Alzheimer’s Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual ScreeningMark Tristan Quimque0Kin Israel Notarte1Arianne Letada2Rey Arturo Fernandez3Delfin Yñigo Pilapil4Kirstin Rhys Pueblos5Jay Carl Agbay6Hans-Martin Dahse7Arlette Wenzel-Storjohann8Deniz Tasdemir9Abbas Khan10Dong-Qing Wei11Allan Patrick Gose Macabeo12Laboratory of Organic Reactivity, Discovery & Synthesis (LORDS), Research Center for Natural & Applied Sciences, University of Santo Tomas, Manila, PhilippinesLaboratory of Organic Reactivity, Discovery & Synthesis (LORDS), Research Center for Natural & Applied Sciences, University of Santo Tomas, Manila, PhilippinesLaboratory of Organic Reactivity, Discovery & Synthesis (LORDS), Research Center for Natural & Applied Sciences, University of Santo Tomas, Manila, PhilippinesLaboratory of Organic Reactivity, Discovery & Synthesis (LORDS), Research Center for Natural & Applied Sciences, University of Santo Tomas, Manila, PhilippinesLaboratory of Organic Reactivity, Discovery & Synthesis (LORDS), Research Center for Natural & Applied Sciences, University of Santo Tomas, Manila, PhilippinesLaboratory of Organic Reactivity, Discovery & Synthesis (LORDS), Research Center for Natural & Applied Sciences, University of Santo Tomas, Manila, PhilippinesDepartment of Chemistry, College of Science and Mathematics, Mindanao State University-Iligan Institute of Technology, Iligan City, PhilippinesLeibniz-Institute for Natural Product Research and Infection Biology, Hans-Knöll-Institute (HKI), Jena, GermanyGEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit, Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Kiel, GermanyGEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit, Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Kiel, GermanyDepartment of Bioinformatics and Biostatistics, State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Bioinformatics and Biostatistics, State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai, ChinaLaboratory of Organic Reactivity, Discovery & Synthesis (LORDS), Research Center for Natural & Applied Sciences, University of Santo Tomas, Manila, Philippineshttps://doi.org/10.1021/acsomega.1c00137
spellingShingle Mark Tristan Quimque
Kin Israel Notarte
Arianne Letada
Rey Arturo Fernandez
Delfin Yñigo Pilapil
Kirstin Rhys Pueblos
Jay Carl Agbay
Hans-Martin Dahse
Arlette Wenzel-Storjohann
Deniz Tasdemir
Abbas Khan
Dong-Qing Wei
Allan Patrick Gose Macabeo
Potential Cancer- and Alzheimer’s Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual Screening
ACS Omega
title Potential Cancer- and Alzheimer’s Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual Screening
title_full Potential Cancer- and Alzheimer’s Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual Screening
title_fullStr Potential Cancer- and Alzheimer’s Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual Screening
title_full_unstemmed Potential Cancer- and Alzheimer’s Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual Screening
title_short Potential Cancer- and Alzheimer’s Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual Screening
title_sort potential cancer and alzheimer s disease targeting phosphodiesterase inhibitors from uvaria alba insights from in vitro and consensus virtual screening
url https://doi.org/10.1021/acsomega.1c00137
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