Supra-barrel Distribution of Directional Tuning for Global Motion in the Mouse Somatosensory Cortex
Summary: Rodents explore their environment with an array of whiskers, inducing complex patterns of whisker deflections. Cortical neuronal networks can extract global properties of tactile scenes. In the primary somatosensory cortex, the information relative to the global direction of a spatiotempora...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-03-01
|
| Series: | Cell Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718303206 |
| _version_ | 1818541539215802368 |
|---|---|
| author | María Eugenia Vilarchao Luc Estebanez Daniel E. Shulz Isabelle Férézou |
| author_facet | María Eugenia Vilarchao Luc Estebanez Daniel E. Shulz Isabelle Férézou |
| author_sort | María Eugenia Vilarchao |
| collection | DOAJ |
| description | Summary: Rodents explore their environment with an array of whiskers, inducing complex patterns of whisker deflections. Cortical neuronal networks can extract global properties of tactile scenes. In the primary somatosensory cortex, the information relative to the global direction of a spatiotemporal sequence of whisker deflections can be extracted at the single neuron level. To further understand how the cortical network integrates multi-whisker inputs, we imaged and recorded the mouse barrel cortex activity evoked by sequences of multi-whisker deflections generating global motions in different directions. A majority of barrel-related cortical columns show a direction preference for global motions with an overall preference for caudo-ventral directions. Responses to global motions being highly sublinear, the identity of the first deflected whiskers is highly salient but does not seem to determine the global direction preference. Our results further demonstrate that the global direction preference is spatially organized throughout the barrel cortex at a supra-columnar scale. : Using voltage-sensitive dye imaging of the mouse barrel cortex, Vilarchao et al. demonstrate the presence of direction selectivity to global motion generated by multi-whisker stimuli. Selectivity to global motion is spatially organized at the supra-columnar scale with an overrepresentation of selectivity to caudo-ventral directions. Keywords: tactile sensory processing, multivibrissal stimulation, primary somatosensory cortex, barrel cortex, voltage-sensitive dye imaging, mouse, extracellular electrophysiological recordings |
| first_indexed | 2024-12-11T22:10:36Z |
| format | Article |
| id | doaj.art-fb4ed57c9fba4f2ca1d444c18e98c213 |
| institution | Directory Open Access Journal |
| issn | 2211-1247 |
| language | English |
| last_indexed | 2024-12-11T22:10:36Z |
| publishDate | 2018-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cell Reports |
| spelling | doaj.art-fb4ed57c9fba4f2ca1d444c18e98c2132022-12-22T00:48:48ZengElsevierCell Reports2211-12472018-03-01221335343547Supra-barrel Distribution of Directional Tuning for Global Motion in the Mouse Somatosensory CortexMaría Eugenia Vilarchao0Luc Estebanez1Daniel E. Shulz2Isabelle Férézou3Unité de Neurosciences, Information et Complexité, Centre National de la Recherche Scientifique, FRE 3693, 91198 Gif-sur-Yvette, FranceUnité de Neurosciences, Information et Complexité, Centre National de la Recherche Scientifique, FRE 3693, 91198 Gif-sur-Yvette, FranceUnité de Neurosciences, Information et Complexité, Centre National de la Recherche Scientifique, FRE 3693, 91198 Gif-sur-Yvette, France; Corresponding authorUnité de Neurosciences, Information et Complexité, Centre National de la Recherche Scientifique, FRE 3693, 91198 Gif-sur-Yvette, France; Corresponding authorSummary: Rodents explore their environment with an array of whiskers, inducing complex patterns of whisker deflections. Cortical neuronal networks can extract global properties of tactile scenes. In the primary somatosensory cortex, the information relative to the global direction of a spatiotemporal sequence of whisker deflections can be extracted at the single neuron level. To further understand how the cortical network integrates multi-whisker inputs, we imaged and recorded the mouse barrel cortex activity evoked by sequences of multi-whisker deflections generating global motions in different directions. A majority of barrel-related cortical columns show a direction preference for global motions with an overall preference for caudo-ventral directions. Responses to global motions being highly sublinear, the identity of the first deflected whiskers is highly salient but does not seem to determine the global direction preference. Our results further demonstrate that the global direction preference is spatially organized throughout the barrel cortex at a supra-columnar scale. : Using voltage-sensitive dye imaging of the mouse barrel cortex, Vilarchao et al. demonstrate the presence of direction selectivity to global motion generated by multi-whisker stimuli. Selectivity to global motion is spatially organized at the supra-columnar scale with an overrepresentation of selectivity to caudo-ventral directions. Keywords: tactile sensory processing, multivibrissal stimulation, primary somatosensory cortex, barrel cortex, voltage-sensitive dye imaging, mouse, extracellular electrophysiological recordingshttp://www.sciencedirect.com/science/article/pii/S2211124718303206 |
| spellingShingle | María Eugenia Vilarchao Luc Estebanez Daniel E. Shulz Isabelle Férézou Supra-barrel Distribution of Directional Tuning for Global Motion in the Mouse Somatosensory Cortex Cell Reports |
| title | Supra-barrel Distribution of Directional Tuning for Global Motion in the Mouse Somatosensory Cortex |
| title_full | Supra-barrel Distribution of Directional Tuning for Global Motion in the Mouse Somatosensory Cortex |
| title_fullStr | Supra-barrel Distribution of Directional Tuning for Global Motion in the Mouse Somatosensory Cortex |
| title_full_unstemmed | Supra-barrel Distribution of Directional Tuning for Global Motion in the Mouse Somatosensory Cortex |
| title_short | Supra-barrel Distribution of Directional Tuning for Global Motion in the Mouse Somatosensory Cortex |
| title_sort | supra barrel distribution of directional tuning for global motion in the mouse somatosensory cortex |
| url | http://www.sciencedirect.com/science/article/pii/S2211124718303206 |
| work_keys_str_mv | AT mariaeugeniavilarchao suprabarreldistributionofdirectionaltuningforglobalmotioninthemousesomatosensorycortex AT lucestebanez suprabarreldistributionofdirectionaltuningforglobalmotioninthemousesomatosensorycortex AT danieleshulz suprabarreldistributionofdirectionaltuningforglobalmotioninthemousesomatosensorycortex AT isabelleferezou suprabarreldistributionofdirectionaltuningforglobalmotioninthemousesomatosensorycortex |