Dosimetric comparison in sparing normal tissue dosage by using auto-SBRT planning in oligo liver tumors
PurposeThe study aimed to compare the dosimetric distribution of VMAT plans by increasing the number of half arcs in liver SBRT and investigate the effect by using automatic plan software in plan optimization.MethodThirty-one patients with oligo liver tumors were randomly selected. VMAT treatment pl...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-11-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1273042/full |
| _version_ | 1797629851732017152 |
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| author | Shu Zhang Shu Zhang Weiyi Zhan Ni Zeng Jiangping Yang Maoqi Xiong Wenjun Liao Nianyong Chen Nianyong Chen Jianghong Xiao |
| author_facet | Shu Zhang Shu Zhang Weiyi Zhan Ni Zeng Jiangping Yang Maoqi Xiong Wenjun Liao Nianyong Chen Nianyong Chen Jianghong Xiao |
| author_sort | Shu Zhang |
| collection | DOAJ |
| description | PurposeThe study aimed to compare the dosimetric distribution of VMAT plans by increasing the number of half arcs in liver SBRT and investigate the effect by using automatic plan software in plan optimization.MethodThirty-one patients with oligo liver tumors were randomly selected. VMAT treatment plans with different numbers of coplanar half arcs were generated.ResultAdding arcs significantly increased the PTV, D2%, D50%, and CI, but sacrificed the plan homogeneity. It also decreased the maximum dose of normal tissues such as the stomach, duodenum, and spinal cord and reduced Dmean, D500cc, and D700cc for the liver. Nevertheless, the diminishing effect gradually decayed into three arcs. Meanwhile, the addition of arcs substantially extended the beam-on time.ConclusionIn the context of SBRT for oligo liver tumors, increasing the number of coplanar half arcs will improve PTV conformity and offer better protection for OARs, albeit at the expense of increased treatment duration. Considering the trade-off between plan quality and treatment efficiency, a three-arc plan may be more suitable for clinical implementation. |
| first_indexed | 2024-03-11T10:58:46Z |
| format | Article |
| id | doaj.art-fb58d72a922b465cab7af086a29f95b3 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-03-11T10:58:46Z |
| publishDate | 2023-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-fb58d72a922b465cab7af086a29f95b32023-11-13T02:54:03ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-11-011310.3389/fonc.2023.12730421273042Dosimetric comparison in sparing normal tissue dosage by using auto-SBRT planning in oligo liver tumorsShu Zhang0Shu Zhang1Weiyi Zhan2Ni Zeng3Jiangping Yang4Maoqi Xiong5Wenjun Liao6Nianyong Chen7Nianyong Chen8Jianghong Xiao9Head and Neck Oncology Department, Cancer Center, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Radiation Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, ChinaCancer Center, West China Hospital, Sichuan University, Chengdu, ChinaHead and Neck Oncology Department, Cancer Center, West China Hospital, Sichuan University, Chengdu, ChinaHead and Neck Oncology Department, Cancer Center, West China Hospital, Sichuan University, Chengdu, ChinaWest China Clinical Skills Training Center, West China School of Medicine/West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, ChinaHead and Neck Oncology Department, Cancer Center, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Radiation Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, ChinaRadiotherapy Physics and Technology Center, Cancer Center, West China Hospital, Sichuan University, Chengdu, ChinaPurposeThe study aimed to compare the dosimetric distribution of VMAT plans by increasing the number of half arcs in liver SBRT and investigate the effect by using automatic plan software in plan optimization.MethodThirty-one patients with oligo liver tumors were randomly selected. VMAT treatment plans with different numbers of coplanar half arcs were generated.ResultAdding arcs significantly increased the PTV, D2%, D50%, and CI, but sacrificed the plan homogeneity. It also decreased the maximum dose of normal tissues such as the stomach, duodenum, and spinal cord and reduced Dmean, D500cc, and D700cc for the liver. Nevertheless, the diminishing effect gradually decayed into three arcs. Meanwhile, the addition of arcs substantially extended the beam-on time.ConclusionIn the context of SBRT for oligo liver tumors, increasing the number of coplanar half arcs will improve PTV conformity and offer better protection for OARs, albeit at the expense of increased treatment duration. Considering the trade-off between plan quality and treatment efficiency, a three-arc plan may be more suitable for clinical implementation.https://www.frontiersin.org/articles/10.3389/fonc.2023.1273042/fullliver cancerdose sparingstereotactic body radiation therapyvolumetric-modulated arc therapyauto-planningnumber of half arcs |
| spellingShingle | Shu Zhang Shu Zhang Weiyi Zhan Ni Zeng Jiangping Yang Maoqi Xiong Wenjun Liao Nianyong Chen Nianyong Chen Jianghong Xiao Dosimetric comparison in sparing normal tissue dosage by using auto-SBRT planning in oligo liver tumors Frontiers in Oncology liver cancer dose sparing stereotactic body radiation therapy volumetric-modulated arc therapy auto-planning number of half arcs |
| title | Dosimetric comparison in sparing normal tissue dosage by using auto-SBRT planning in oligo liver tumors |
| title_full | Dosimetric comparison in sparing normal tissue dosage by using auto-SBRT planning in oligo liver tumors |
| title_fullStr | Dosimetric comparison in sparing normal tissue dosage by using auto-SBRT planning in oligo liver tumors |
| title_full_unstemmed | Dosimetric comparison in sparing normal tissue dosage by using auto-SBRT planning in oligo liver tumors |
| title_short | Dosimetric comparison in sparing normal tissue dosage by using auto-SBRT planning in oligo liver tumors |
| title_sort | dosimetric comparison in sparing normal tissue dosage by using auto sbrt planning in oligo liver tumors |
| topic | liver cancer dose sparing stereotactic body radiation therapy volumetric-modulated arc therapy auto-planning number of half arcs |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1273042/full |
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