EOSINOPHILIC INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT AND FOOD ALLERGY AMONG CHILDREN

<em>Within the structure of the inflammatory diseases of the gastrointestinal tract among children, one may single out a specific group of the chronic pathology of the digestive apparatus — eosinophilic diseases of the gastrointestinal tract and gastroenterological manifestations of the food a...

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Main Authors: P.V. Shumilov, M.I. Dubrovskaya, O.V. Yudina, Yu.G. Mukhina, A.S. Tertychnyi
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2007-01-01
Series:Вопросы современной педиатрии
Online Access:http://vsp.spr-journal.ru:80/jour/article/view/1250
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author P.V. Shumilov
M.I. Dubrovskaya
O.V. Yudina
Yu.G. Mukhina
A.S. Tertychnyi
author_facet P.V. Shumilov
M.I. Dubrovskaya
O.V. Yudina
Yu.G. Mukhina
A.S. Tertychnyi
author_sort P.V. Shumilov
collection DOAJ
description <em>Within the structure of the inflammatory diseases of the gastrointestinal tract among children, one may single out a specific group of the chronic pathology of the digestive apparatus — eosinophilic diseases of the gastrointestinal tract and gastroenterological manifestations of the food allergy. The food allergy is characterized by the pathologic immune reactivity among commonly genetically predisposed people. Depending on the peculiarities of the immune reactivity of a sick person and the nature of the allergen, the allergic reaction may evolve with primary involvement of the different mechanisms or th2 IgE-mediated, or Th1 non-igecmediated. Clinical picture of the food allergy is the manifestation of the immunoinflammatory process caused by the interaction of the food antigens with the structures of the lymphoid tissues associated with the mucous membranes of this or that target organ. The morphological basis of the clinical picture is mostly immune inflammation with primarily eosinophilic tissue infiltration. The eosinophilic lesions of the gastrointestinal tract include eosinophilic esophagitis, eosinophilic gastroenteritis, eosinophilic enteritis, eosinophilic colitis, eosinophilic proctitis and other states. During the food allergy each of the clinical forms of the gastrointestinal tract lesion has its own peculiarities with regards to the primary development mechanism, age of manifestation, character of the run and behaviour tactics.</em><br /><strong><em>Key words: eosinophilic inflammation, esophagitis, gastroenteritis, colitis, food allergy.</em></strong>
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spelling doaj.art-fb58d8479b0c4cb39d5bfb66399ad9172023-09-02T23:02:42Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352007-01-016444531250EOSINOPHILIC INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT AND FOOD ALLERGY AMONG CHILDRENP.V. Shumilov0M.I. Dubrovskaya1O.V. Yudina2Yu.G. Mukhina3A.S. Tertychnyi4Russian State Medical University, MoscowRussian State Medical University, MoscowRussian State Medical University, MoscowRussian State Medical University, MoscowRussian State Medical University, Moscow<em>Within the structure of the inflammatory diseases of the gastrointestinal tract among children, one may single out a specific group of the chronic pathology of the digestive apparatus — eosinophilic diseases of the gastrointestinal tract and gastroenterological manifestations of the food allergy. The food allergy is characterized by the pathologic immune reactivity among commonly genetically predisposed people. Depending on the peculiarities of the immune reactivity of a sick person and the nature of the allergen, the allergic reaction may evolve with primary involvement of the different mechanisms or th2 IgE-mediated, or Th1 non-igecmediated. Clinical picture of the food allergy is the manifestation of the immunoinflammatory process caused by the interaction of the food antigens with the structures of the lymphoid tissues associated with the mucous membranes of this or that target organ. The morphological basis of the clinical picture is mostly immune inflammation with primarily eosinophilic tissue infiltration. The eosinophilic lesions of the gastrointestinal tract include eosinophilic esophagitis, eosinophilic gastroenteritis, eosinophilic enteritis, eosinophilic colitis, eosinophilic proctitis and other states. During the food allergy each of the clinical forms of the gastrointestinal tract lesion has its own peculiarities with regards to the primary development mechanism, age of manifestation, character of the run and behaviour tactics.</em><br /><strong><em>Key words: eosinophilic inflammation, esophagitis, gastroenteritis, colitis, food allergy.</em></strong>http://vsp.spr-journal.ru:80/jour/article/view/1250
spellingShingle P.V. Shumilov
M.I. Dubrovskaya
O.V. Yudina
Yu.G. Mukhina
A.S. Tertychnyi
EOSINOPHILIC INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT AND FOOD ALLERGY AMONG CHILDREN
Вопросы современной педиатрии
title EOSINOPHILIC INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT AND FOOD ALLERGY AMONG CHILDREN
title_full EOSINOPHILIC INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT AND FOOD ALLERGY AMONG CHILDREN
title_fullStr EOSINOPHILIC INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT AND FOOD ALLERGY AMONG CHILDREN
title_full_unstemmed EOSINOPHILIC INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT AND FOOD ALLERGY AMONG CHILDREN
title_short EOSINOPHILIC INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT AND FOOD ALLERGY AMONG CHILDREN
title_sort eosinophilic inflammatory diseases of the gastrointestinal tract and food allergy among children
url http://vsp.spr-journal.ru:80/jour/article/view/1250
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