Using Mixed Integer Linear Programming Model For Beam Angle And Fluence Map Optimization In Intensity- Modulated Radiation Therapy
Introdution: Intensity- modulated radiation therapy is one of the treatment methods for cancer tumors. The effectiveness of this method is dependent on the accuracy and treatment planning quality. Therefore, there is a need for a plan to select the angle and intensity simultaneous optimum of radiati...
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| Format: | Article |
| Language: | fas |
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Shahid Sadoughi University of Medical Sciences
2018-04-01
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| Series: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
| Subjects: | |
| Online Access: | http://jssu.ssu.ac.ir/browse.php?a_code=A-10-3320-1&slc_lang=en&sid=1 |
| _version_ | 1819268141323124736 |
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| author | Ahmad Sadegheih Maryam Savari Abolfazl Nickfarjam |
| author_facet | Ahmad Sadegheih Maryam Savari Abolfazl Nickfarjam |
| author_sort | Ahmad Sadegheih |
| collection | DOAJ |
| description | Introdution: Intensity- modulated radiation therapy is one of the treatment methods for cancer tumors. The effectiveness of this method is dependent on the accuracy and treatment planning quality. Therefore, there is a need for a plan to select the angle and intensity simultaneous optimum of radiation.
Methods: In this study, an mixed integer linear programming model was proposed for simultaneous optimization of angles and intensity in the GAMS programming environment.To implement the model, after the patient's CT was prepared, the organ cantoring was performed by CERR software and the Influence Matrix was obtained for each organ. After collecting the inputs of the problem, in order to obtain the desired outputs, was used from The GAMS software from the CPLEX solver.
Results: Finally, the actual case of head and neck cancer is analyzed to demonstrate the effectiveness of the model. From the angle of the candidate, ، is chosen as the optimal radiation angles. The maximum dose received by the brainstem was 3. 999, Mandible 70, LeftOrbit 0.026, RightOrbit 0.440, Parotid Gland 0.881, OpticChiasm 0.177, OpticNerves 0.167, spinalcord 9.929 Gray and the minimum dose received by the tumor is 70 Gray. Also, the optimal amount of intensity for implementing the treatment plan on the patient is achieved.
Conclusion: The dose received by each organ was significantly improved compared to prescribing doses. Similarly, the comparison of the Dose Volume Histogram obtained by solving a common problem with the model and software CERR, Represents the optimal performance of the model, which improves the security rate and reduces the cost for healthy tissues. |
| first_indexed | 2024-12-23T21:28:21Z |
| format | Article |
| id | doaj.art-fb5901892d66493dadec50781719a6b7 |
| institution | Directory Open Access Journal |
| issn | 2228-5741 2228-5733 |
| language | fas |
| last_indexed | 2024-12-23T21:28:21Z |
| publishDate | 2018-04-01 |
| publisher | Shahid Sadoughi University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
| spelling | doaj.art-fb5901892d66493dadec50781719a6b72022-12-21T17:30:33ZfasShahid Sadoughi University of Medical SciencesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd2228-57412228-57332018-04-012612739Using Mixed Integer Linear Programming Model For Beam Angle And Fluence Map Optimization In Intensity- Modulated Radiation TherapyAhmad Sadegheih0Maryam Savari1Abolfazl Nickfarjam2 Department of Industrial Engineering, Faculty of Industry, University of Yazd , Iran 2Department of Industrial Engineering, University of Yazd, Iran Department of Medical physics, Radiotherapy Research Center Faculty of Medicine, Shahid Sadoughi University of Medical Sciences and Health Services ,Yazd, Iran Introdution: Intensity- modulated radiation therapy is one of the treatment methods for cancer tumors. The effectiveness of this method is dependent on the accuracy and treatment planning quality. Therefore, there is a need for a plan to select the angle and intensity simultaneous optimum of radiation. Methods: In this study, an mixed integer linear programming model was proposed for simultaneous optimization of angles and intensity in the GAMS programming environment.To implement the model, after the patient's CT was prepared, the organ cantoring was performed by CERR software and the Influence Matrix was obtained for each organ. After collecting the inputs of the problem, in order to obtain the desired outputs, was used from The GAMS software from the CPLEX solver. Results: Finally, the actual case of head and neck cancer is analyzed to demonstrate the effectiveness of the model. From the angle of the candidate, ، is chosen as the optimal radiation angles. The maximum dose received by the brainstem was 3. 999, Mandible 70, LeftOrbit 0.026, RightOrbit 0.440, Parotid Gland 0.881, OpticChiasm 0.177, OpticNerves 0.167, spinalcord 9.929 Gray and the minimum dose received by the tumor is 70 Gray. Also, the optimal amount of intensity for implementing the treatment plan on the patient is achieved. Conclusion: The dose received by each organ was significantly improved compared to prescribing doses. Similarly, the comparison of the Dose Volume Histogram obtained by solving a common problem with the model and software CERR, Represents the optimal performance of the model, which improves the security rate and reduces the cost for healthy tissues.http://jssu.ssu.ac.ir/browse.php?a_code=A-10-3320-1&slc_lang=en&sid=1Intensity- Modulated Radiation Therapy Fluence Map Optimization Beam Angle Optimization Mixed Integer Linear Programming Model |
| spellingShingle | Ahmad Sadegheih Maryam Savari Abolfazl Nickfarjam Using Mixed Integer Linear Programming Model For Beam Angle And Fluence Map Optimization In Intensity- Modulated Radiation Therapy Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd Intensity- Modulated Radiation Therapy Fluence Map Optimization Beam Angle Optimization Mixed Integer Linear Programming Model |
| title | Using Mixed Integer Linear Programming Model For Beam Angle And Fluence Map Optimization In Intensity- Modulated Radiation Therapy |
| title_full | Using Mixed Integer Linear Programming Model For Beam Angle And Fluence Map Optimization In Intensity- Modulated Radiation Therapy |
| title_fullStr | Using Mixed Integer Linear Programming Model For Beam Angle And Fluence Map Optimization In Intensity- Modulated Radiation Therapy |
| title_full_unstemmed | Using Mixed Integer Linear Programming Model For Beam Angle And Fluence Map Optimization In Intensity- Modulated Radiation Therapy |
| title_short | Using Mixed Integer Linear Programming Model For Beam Angle And Fluence Map Optimization In Intensity- Modulated Radiation Therapy |
| title_sort | using mixed integer linear programming model for beam angle and fluence map optimization in intensity modulated radiation therapy |
| topic | Intensity- Modulated Radiation Therapy Fluence Map Optimization Beam Angle Optimization Mixed Integer Linear Programming Model |
| url | http://jssu.ssu.ac.ir/browse.php?a_code=A-10-3320-1&slc_lang=en&sid=1 |
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