Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b

Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b

The activation of the renin-angiotensin system (RAS) induced by increased angiotensin II (AngII) levels has been implicated in muscle atrophy, which is involved in the pathogenesis of congestive heart failure. Although peroxisome proliferator-activated receptor gamma (PPARγ) activation can suppress...

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Bibliographic Details
Main Authors: Jin Li, Tingting Yang, Zhao Sha, Haifei Tang, Xuejiao Hua, Lijun Wang, Zitong Wang, Ziyu Gao, Joost P.G. Sluijter, Glenn C. Rowe, Saumya Das, Liming Yang, Junjie Xiao
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
muscle atrophy
angiotensin II
PPARγ
miR-29b
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120303966

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