The results of pancreatic surgery in Inuit patients from Greenland 1999-2022
ABSTRACTThe study evaluates the outcome after surgery for pancreatic and periampullary tumors in Greenlandic Inuit with overall survival (OS) of pancreatic ductal adenocarcinoma (PDAC) as secondary outcome. Results were compared with Danish patients with an identical tumor stage and age operated at...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2023-12-01
|
| Series: | International Journal of Circumpolar Health |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/22423982.2023.2208392 |
| _version_ | 1797385604714987520 |
|---|---|
| author | Kerstin Almdal Jan Storkholm Simon Bernth-Andersen Carsten Palnaes Hansen |
| author_facet | Kerstin Almdal Jan Storkholm Simon Bernth-Andersen Carsten Palnaes Hansen |
| author_sort | Kerstin Almdal |
| collection | DOAJ |
| description | ABSTRACTThe study evaluates the outcome after surgery for pancreatic and periampullary tumors in Greenlandic Inuit with overall survival (OS) of pancreatic ductal adenocarcinoma (PDAC) as secondary outcome. Results were compared with Danish patients with an identical tumor stage and age operated at the same hospital during the same period from 31. January 1999 to 31. January 2021. Follow up was minimum one year. Preoperative health data shoved a higher rate of smoking among Greenlandic patients, but a lower preoperative comorbidity than in Danish patients. Patients from Greenland had a lower resection rate and a higher rate of palliative operations. Postoperative complications and in-hospital mortality were not significantly different. Adjuvant oncologic treatment was well accepted by Greenlandic patients but less common in a palliative setting than in Danish patients. The one, two, and five-year survival in Greenlandic and Danish patients after radical operation for PDAC was 54.4% vs. 74.6%, 23.4% vs. 48.6%, and 0.0% vs. 23.4%, respectively. The overall survival with non-resectable PDAC was 5.9 and 8.8 months, respectively. It is concluded that although patients from Greenland have the same access to specialized treatment, the outcome after treatment for pancreatic and periampullary cancer is less favorable than in Danish patients. |
| first_indexed | 2024-03-08T21:56:34Z |
| format | Article |
| id | doaj.art-fb5c002591204c1fa404d317213f14d9 |
| institution | Directory Open Access Journal |
| issn | 2242-3982 |
| language | English |
| last_indexed | 2024-03-08T21:56:34Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Circumpolar Health |
| spelling | doaj.art-fb5c002591204c1fa404d317213f14d92023-12-19T21:44:11ZengTaylor & Francis GroupInternational Journal of Circumpolar Health2242-39822023-12-0182110.1080/22423982.2023.2208392The results of pancreatic surgery in Inuit patients from Greenland 1999-2022Kerstin Almdal0Jan Storkholm1Simon Bernth-Andersen2Carsten Palnaes Hansen3Department of Surgery, Dronning Ingrid’s Hospital, Nuuk, GreenlandDepartment of Surgery and Transplantation, Rigshospitalet, Copenhagen, DenmarkDepartment of Surgery, Dronning Ingrid’s Hospital, Nuuk, GreenlandDepartment of Surgery and Transplantation, Rigshospitalet, Copenhagen, DenmarkABSTRACTThe study evaluates the outcome after surgery for pancreatic and periampullary tumors in Greenlandic Inuit with overall survival (OS) of pancreatic ductal adenocarcinoma (PDAC) as secondary outcome. Results were compared with Danish patients with an identical tumor stage and age operated at the same hospital during the same period from 31. January 1999 to 31. January 2021. Follow up was minimum one year. Preoperative health data shoved a higher rate of smoking among Greenlandic patients, but a lower preoperative comorbidity than in Danish patients. Patients from Greenland had a lower resection rate and a higher rate of palliative operations. Postoperative complications and in-hospital mortality were not significantly different. Adjuvant oncologic treatment was well accepted by Greenlandic patients but less common in a palliative setting than in Danish patients. The one, two, and five-year survival in Greenlandic and Danish patients after radical operation for PDAC was 54.4% vs. 74.6%, 23.4% vs. 48.6%, and 0.0% vs. 23.4%, respectively. The overall survival with non-resectable PDAC was 5.9 and 8.8 months, respectively. It is concluded that although patients from Greenland have the same access to specialized treatment, the outcome after treatment for pancreatic and periampullary cancer is less favorable than in Danish patients.https://www.tandfonline.com/doi/10.1080/22423982.2023.2208392Pancreatic surgerycancerInuitGreenlandoutcome |
| spellingShingle | Kerstin Almdal Jan Storkholm Simon Bernth-Andersen Carsten Palnaes Hansen The results of pancreatic surgery in Inuit patients from Greenland 1999-2022 International Journal of Circumpolar Health Pancreatic surgery cancer Inuit Greenland outcome |
| title | The results of pancreatic surgery in Inuit patients from Greenland 1999-2022 |
| title_full | The results of pancreatic surgery in Inuit patients from Greenland 1999-2022 |
| title_fullStr | The results of pancreatic surgery in Inuit patients from Greenland 1999-2022 |
| title_full_unstemmed | The results of pancreatic surgery in Inuit patients from Greenland 1999-2022 |
| title_short | The results of pancreatic surgery in Inuit patients from Greenland 1999-2022 |
| title_sort | results of pancreatic surgery in inuit patients from greenland 1999 2022 |
| topic | Pancreatic surgery cancer Inuit Greenland outcome |
| url | https://www.tandfonline.com/doi/10.1080/22423982.2023.2208392 |
| work_keys_str_mv | AT kerstinalmdal theresultsofpancreaticsurgeryininuitpatientsfromgreenland19992022 AT janstorkholm theresultsofpancreaticsurgeryininuitpatientsfromgreenland19992022 AT simonbernthandersen theresultsofpancreaticsurgeryininuitpatientsfromgreenland19992022 AT carstenpalnaeshansen theresultsofpancreaticsurgeryininuitpatientsfromgreenland19992022 AT kerstinalmdal resultsofpancreaticsurgeryininuitpatientsfromgreenland19992022 AT janstorkholm resultsofpancreaticsurgeryininuitpatientsfromgreenland19992022 AT simonbernthandersen resultsofpancreaticsurgeryininuitpatientsfromgreenland19992022 AT carstenpalnaeshansen resultsofpancreaticsurgeryininuitpatientsfromgreenland19992022 |