Endothelial β‐arrestins regulate mechanotransduction by the type II bone morphogenetic protein receptor in primary cilia

Endothelial β‐arrestins regulate mechanotransduction by the type II bone morphogenetic protein receptor in primary cilia

Abstract Modulation of endothelial cell behavior and phenotype by hemodynamic forces involves many signaling components, including cell surface receptors, intracellular signaling intermediaries, transcription factors, and epigenetic elements. Many of the signaling mechanisms that underlie mechanotra...

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Bibliographic Details
Main Authors: Saejeong Park, Zhiyuan Ma, Georgia Zarkada, Irinna Papangeli, Sarin Paluri, Nour Nazo, Felix Rivera‐Molina, Derek Toomre, Sudarshan Rajagopal, Hyung J. Chun
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Pulmonary Circulation
Subjects:
beta‐arrestin
BMPR2
endothelial cells
primary cilia
shear stress
Online Access:https://doi.org/10.1002/pul2.12167

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