Retrospective analysis of demographic, clinical, and histopathological parameters in patients with basal cell carcinoma
Background: Basal cell carcinoma (BCC) is a common malignancy among light-skin races. Chronic solar exposure is the most important precipitating factor. In India, BCC is the second in order among the nonmelanoma skin cancers, the first being squamous cell carcinoma. Actual incidence and prevalence o...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2019-01-01
|
| Series: | Clinical Dermatology Review |
| Subjects: | |
| Online Access: | http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2019;volume=3;issue=2;spage=130;epage=135;aulast=Palit |
| _version_ | 1818455734268985344 |
|---|---|
| author | Aparna Palit P Ram Sushruth Keshavmurthy A Adya Ajit B Janagond Niranjan S Deshmukh Arun C Inamadar |
| author_facet | Aparna Palit P Ram Sushruth Keshavmurthy A Adya Ajit B Janagond Niranjan S Deshmukh Arun C Inamadar |
| author_sort | Aparna Palit |
| collection | DOAJ |
| description | Background: Basal cell carcinoma (BCC) is a common malignancy among light-skin races. Chronic solar exposure is the most important precipitating factor. In India, BCC is the second in order among the nonmelanoma skin cancers, the first being squamous cell carcinoma. Actual incidence and prevalence of this tumor in various geographical regions of India remain undefined. Aim: The aim is to study the demographic, clinical, and histopathological parameters of the patients suffering from BCC residing in a rural area of northern Karnataka. Materials and Methods: Retrospective data analysis of the patients suffering from BCC was performed from the records of dermatology outpatients' department of a tertiary healthcare center in north Karnataka. Results: A total of 41 cases of BCC were examined during 12 years. The duration of the lesions varied from 6 months to 20 years. Female patients outnumbered males in a ratio of 3.36:1. Majority of the patients were homemakers and agricultural workers. Nodular, noduloulcerative, and pigmented BCC were the most common clinical pattern and 9 (28.1%) cases of morpheaform BCC were recorded. Four patients had genodermatoses; three were xeroderma pigmentosum and one case of nevoid BCC syndrome. These patients had multiple lesions of BCC. Classical histopathological features were recorded in all cases. One specimen showed evidence of metatypical epithelioma. Conclusion: Most of the patients in this series belonged to the rural part of North Karnataka, predominantly homemakers and agricultural workers. Females were more commonly affected, attributable to the intermittent type of solar exposure. Morpheaform BCC accounted for less than a quarter of cases, and multiple BCCs associated with genodermatoses were seen in four cases. |
| first_indexed | 2024-12-14T22:15:29Z |
| format | Article |
| id | doaj.art-fb6202162a234209a8060b7f7b7423ec |
| institution | Directory Open Access Journal |
| issn | 2542-551X 2542-5528 |
| language | English |
| last_indexed | 2024-12-14T22:15:29Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Clinical Dermatology Review |
| spelling | doaj.art-fb6202162a234209a8060b7f7b7423ec2022-12-21T22:45:38ZengWolters Kluwer Medknow PublicationsClinical Dermatology Review2542-551X2542-55282019-01-013213013510.4103/CDR.CDR_3_19Retrospective analysis of demographic, clinical, and histopathological parameters in patients with basal cell carcinomaAparna PalitP Ram SushruthKeshavmurthy A AdyaAjit B JanagondNiranjan S DeshmukhArun C InamadarBackground: Basal cell carcinoma (BCC) is a common malignancy among light-skin races. Chronic solar exposure is the most important precipitating factor. In India, BCC is the second in order among the nonmelanoma skin cancers, the first being squamous cell carcinoma. Actual incidence and prevalence of this tumor in various geographical regions of India remain undefined. Aim: The aim is to study the demographic, clinical, and histopathological parameters of the patients suffering from BCC residing in a rural area of northern Karnataka. Materials and Methods: Retrospective data analysis of the patients suffering from BCC was performed from the records of dermatology outpatients' department of a tertiary healthcare center in north Karnataka. Results: A total of 41 cases of BCC were examined during 12 years. The duration of the lesions varied from 6 months to 20 years. Female patients outnumbered males in a ratio of 3.36:1. Majority of the patients were homemakers and agricultural workers. Nodular, noduloulcerative, and pigmented BCC were the most common clinical pattern and 9 (28.1%) cases of morpheaform BCC were recorded. Four patients had genodermatoses; three were xeroderma pigmentosum and one case of nevoid BCC syndrome. These patients had multiple lesions of BCC. Classical histopathological features were recorded in all cases. One specimen showed evidence of metatypical epithelioma. Conclusion: Most of the patients in this series belonged to the rural part of North Karnataka, predominantly homemakers and agricultural workers. Females were more commonly affected, attributable to the intermittent type of solar exposure. Morpheaform BCC accounted for less than a quarter of cases, and multiple BCCs associated with genodermatoses were seen in four cases.http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2019;volume=3;issue=2;spage=130;epage=135;aulast=Palitbasal cell carcinomanevoid basal cell carcinoma syndromenonmelanoma skin cancerxeroderma pigmentosum |
| spellingShingle | Aparna Palit P Ram Sushruth Keshavmurthy A Adya Ajit B Janagond Niranjan S Deshmukh Arun C Inamadar Retrospective analysis of demographic, clinical, and histopathological parameters in patients with basal cell carcinoma Clinical Dermatology Review basal cell carcinoma nevoid basal cell carcinoma syndrome nonmelanoma skin cancer xeroderma pigmentosum |
| title | Retrospective analysis of demographic, clinical, and histopathological parameters in patients with basal cell carcinoma |
| title_full | Retrospective analysis of demographic, clinical, and histopathological parameters in patients with basal cell carcinoma |
| title_fullStr | Retrospective analysis of demographic, clinical, and histopathological parameters in patients with basal cell carcinoma |
| title_full_unstemmed | Retrospective analysis of demographic, clinical, and histopathological parameters in patients with basal cell carcinoma |
| title_short | Retrospective analysis of demographic, clinical, and histopathological parameters in patients with basal cell carcinoma |
| title_sort | retrospective analysis of demographic clinical and histopathological parameters in patients with basal cell carcinoma |
| topic | basal cell carcinoma nevoid basal cell carcinoma syndrome nonmelanoma skin cancer xeroderma pigmentosum |
| url | http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2019;volume=3;issue=2;spage=130;epage=135;aulast=Palit |
| work_keys_str_mv | AT aparnapalit retrospectiveanalysisofdemographicclinicalandhistopathologicalparametersinpatientswithbasalcellcarcinoma AT pramsushruth retrospectiveanalysisofdemographicclinicalandhistopathologicalparametersinpatientswithbasalcellcarcinoma AT keshavmurthyaadya retrospectiveanalysisofdemographicclinicalandhistopathologicalparametersinpatientswithbasalcellcarcinoma AT ajitbjanagond retrospectiveanalysisofdemographicclinicalandhistopathologicalparametersinpatientswithbasalcellcarcinoma AT niranjansdeshmukh retrospectiveanalysisofdemographicclinicalandhistopathologicalparametersinpatientswithbasalcellcarcinoma AT aruncinamadar retrospectiveanalysisofdemographicclinicalandhistopathologicalparametersinpatientswithbasalcellcarcinoma |