Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report

Abstract Background Diphtheria is caused by Corynebacterium diphtheriae. Although waning in incidence diphtheria can cause severe disease as in this rare Swedish case with several complications. Case presentation A 55-year old male presented to the emergency room with severe respiratory symptoms and...

Full description

Bibliographic Details
Main Authors: Sten Skogmar, Johan Tham
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Infectious Diseases
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12879-018-3264-9
_version_ 1818528812587024384
author Sten Skogmar
Johan Tham
author_facet Sten Skogmar
Johan Tham
author_sort Sten Skogmar
collection DOAJ
description Abstract Background Diphtheria is caused by Corynebacterium diphtheriae. Although waning in incidence diphtheria can cause severe disease as in this rare Swedish case with several complications. Case presentation A 55-year old male presented to the emergency room with severe respiratory symptoms and greyish membranes in the airways, which turned positive for C. diphtheriae. He was put on ventilator support and remained hospitalized for three months. During care he developed myocarditis and severe neurological disease and he was also co-infected with tuberculosis. The patient was discharged with a favorable outcome. Conclusions Diphtheria should be suspected in patients with life-threatening pneumonia especially if the patient has a history of travelling. Our patient was not treated with diphtheria anti-toxin (DAT) which may have contributed to the severity of the disease.
first_indexed 2024-12-11T06:54:53Z
format Article
id doaj.art-fb6344df5fda4953b8173741e40ccea1
institution Directory Open Access Journal
issn 1471-2334
language English
last_indexed 2024-12-11T06:54:53Z
publishDate 2018-07-01
publisher BMC
record_format Article
series BMC Infectious Diseases
spelling doaj.art-fb6344df5fda4953b8173741e40ccea12022-12-22T01:16:48ZengBMCBMC Infectious Diseases1471-23342018-07-011811510.1186/s12879-018-3264-9Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case reportSten Skogmar0Johan Tham1Department of Translational Medicine, Clinical Infection Medicine, Lund University, Skåne University HospitalDepartment of Translational Medicine, Clinical Infection Medicine, Lund University, Skåne University HospitalAbstract Background Diphtheria is caused by Corynebacterium diphtheriae. Although waning in incidence diphtheria can cause severe disease as in this rare Swedish case with several complications. Case presentation A 55-year old male presented to the emergency room with severe respiratory symptoms and greyish membranes in the airways, which turned positive for C. diphtheriae. He was put on ventilator support and remained hospitalized for three months. During care he developed myocarditis and severe neurological disease and he was also co-infected with tuberculosis. The patient was discharged with a favorable outcome. Conclusions Diphtheria should be suspected in patients with life-threatening pneumonia especially if the patient has a history of travelling. Our patient was not treated with diphtheria anti-toxin (DAT) which may have contributed to the severity of the disease.http://link.springer.com/article/10.1186/s12879-018-3264-9DiphtheriaCorynebacterium diphtheriaeRespiratory diseaseNeurological manifestationsMyocarditisTuberculosis
spellingShingle Sten Skogmar
Johan Tham
Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
BMC Infectious Diseases
Diphtheria
Corynebacterium diphtheriae
Respiratory disease
Neurological manifestations
Myocarditis
Tuberculosis
title Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
title_full Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
title_fullStr Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
title_full_unstemmed Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
title_short Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
title_sort severe diphtheria with neurologic and myocardial involvement in a swedish patient a case report
topic Diphtheria
Corynebacterium diphtheriae
Respiratory disease
Neurological manifestations
Myocarditis
Tuberculosis
url http://link.springer.com/article/10.1186/s12879-018-3264-9
work_keys_str_mv AT stenskogmar severediphtheriawithneurologicandmyocardialinvolvementinaswedishpatientacasereport
AT johantham severediphtheriawithneurologicandmyocardialinvolvementinaswedishpatientacasereport