Nanohydroxyapatite Electrodeposition onto Electrospun Nanofibers: Technique Overview and Tissue Engineering Applications
Nanocomposite scaffolds based on the combination of polymeric nanofibers with nanohydroxyapatite are a promising approach within tissue engineering. With this strategy, it is possible to synthesize nanobiomaterials that combine the well-known benefits and advantages of polymer-based nanofibers with...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-10-01
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| Series: | Bioengineering |
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| Online Access: | https://www.mdpi.com/2306-5354/8/11/151 |
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| author | Thiago Domingues Stocco Pedro José Gomes Rodrigues Mauricio Augusto de Almeida Filho Anderson Oliveira Lobo |
| author_facet | Thiago Domingues Stocco Pedro José Gomes Rodrigues Mauricio Augusto de Almeida Filho Anderson Oliveira Lobo |
| author_sort | Thiago Domingues Stocco |
| collection | DOAJ |
| description | Nanocomposite scaffolds based on the combination of polymeric nanofibers with nanohydroxyapatite are a promising approach within tissue engineering. With this strategy, it is possible to synthesize nanobiomaterials that combine the well-known benefits and advantages of polymer-based nanofibers with the osteointegrative, osteoinductive, and osteoconductive properties of nanohydroxyapatite, generating scaffolds with great potential for applications in regenerative medicine, especially as support for bone growth and regeneration. However, as efficiently incorporating nanohydroxyapatite into polymeric nanofibers is still a challenge, new methodologies have emerged for this purpose, such as electrodeposition, a fast, low-cost, adjustable, and reproducible technique capable of depositing coatings of nanohydroxyapatite on the outside of fibers, to improve scaffold bioactivity and cell–biomaterial interactions. In this short review paper, we provide an overview of the electrodeposition method, as well as a detailed discussion about the process of electrodepositing nanohydroxyapatite on the surface of polymer electrospun nanofibers. In addition, we present the main findings of the recent applications of polymeric micro/nanofibrous scaffolds coated with electrodeposited nanohydroxyapatite in tissue engineering. In conclusion, comments are provided about the future direction of nanohydroxyapatite electrodeposition onto polymeric nanofibers. |
| first_indexed | 2024-03-10T05:42:48Z |
| format | Article |
| id | doaj.art-fb639c2f8d3d4b1c93d00c2b68418c59 |
| institution | Directory Open Access Journal |
| issn | 2306-5354 |
| language | English |
| last_indexed | 2024-03-10T05:42:48Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Bioengineering |
| spelling | doaj.art-fb639c2f8d3d4b1c93d00c2b68418c592023-11-22T22:26:19ZengMDPI AGBioengineering2306-53542021-10-0181115110.3390/bioengineering8110151Nanohydroxyapatite Electrodeposition onto Electrospun Nanofibers: Technique Overview and Tissue Engineering ApplicationsThiago Domingues Stocco0Pedro José Gomes Rodrigues1Mauricio Augusto de Almeida Filho2Anderson Oliveira Lobo3Faculty of Medical Sciences, State University of Campinas, Campinas 13083-877, BrazilLIMAV—Interdisciplinary Laboratory for Advanced Materials, BioMatLab, UFPI—Federal University of Piauí, Teresina 64049-550, BrazilLIMAV—Interdisciplinary Laboratory for Advanced Materials, BioMatLab, UFPI—Federal University of Piauí, Teresina 64049-550, BrazilLIMAV—Interdisciplinary Laboratory for Advanced Materials, BioMatLab, UFPI—Federal University of Piauí, Teresina 64049-550, BrazilNanocomposite scaffolds based on the combination of polymeric nanofibers with nanohydroxyapatite are a promising approach within tissue engineering. With this strategy, it is possible to synthesize nanobiomaterials that combine the well-known benefits and advantages of polymer-based nanofibers with the osteointegrative, osteoinductive, and osteoconductive properties of nanohydroxyapatite, generating scaffolds with great potential for applications in regenerative medicine, especially as support for bone growth and regeneration. However, as efficiently incorporating nanohydroxyapatite into polymeric nanofibers is still a challenge, new methodologies have emerged for this purpose, such as electrodeposition, a fast, low-cost, adjustable, and reproducible technique capable of depositing coatings of nanohydroxyapatite on the outside of fibers, to improve scaffold bioactivity and cell–biomaterial interactions. In this short review paper, we provide an overview of the electrodeposition method, as well as a detailed discussion about the process of electrodepositing nanohydroxyapatite on the surface of polymer electrospun nanofibers. In addition, we present the main findings of the recent applications of polymeric micro/nanofibrous scaffolds coated with electrodeposited nanohydroxyapatite in tissue engineering. In conclusion, comments are provided about the future direction of nanohydroxyapatite electrodeposition onto polymeric nanofibers.https://www.mdpi.com/2306-5354/8/11/151nanohydroxyapatiteelectrodepositionpolymeric nanofibersscaffoldtissue engineering |
| spellingShingle | Thiago Domingues Stocco Pedro José Gomes Rodrigues Mauricio Augusto de Almeida Filho Anderson Oliveira Lobo Nanohydroxyapatite Electrodeposition onto Electrospun Nanofibers: Technique Overview and Tissue Engineering Applications Bioengineering nanohydroxyapatite electrodeposition polymeric nanofibers scaffold tissue engineering |
| title | Nanohydroxyapatite Electrodeposition onto Electrospun Nanofibers: Technique Overview and Tissue Engineering Applications |
| title_full | Nanohydroxyapatite Electrodeposition onto Electrospun Nanofibers: Technique Overview and Tissue Engineering Applications |
| title_fullStr | Nanohydroxyapatite Electrodeposition onto Electrospun Nanofibers: Technique Overview and Tissue Engineering Applications |
| title_full_unstemmed | Nanohydroxyapatite Electrodeposition onto Electrospun Nanofibers: Technique Overview and Tissue Engineering Applications |
| title_short | Nanohydroxyapatite Electrodeposition onto Electrospun Nanofibers: Technique Overview and Tissue Engineering Applications |
| title_sort | nanohydroxyapatite electrodeposition onto electrospun nanofibers technique overview and tissue engineering applications |
| topic | nanohydroxyapatite electrodeposition polymeric nanofibers scaffold tissue engineering |
| url | https://www.mdpi.com/2306-5354/8/11/151 |
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