Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine response in adults with predominantly antibody deficiency

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine response in adults with predominantly antibody deficiency

Background: Patients with predominantly antibody deficiency (PAD) have lower anti–severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike antibody levels after initial 2-dose SARS-CoV-2 vaccination than healthy controls do; however, the anti-spike antibody responses and neutralization fun...

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Main Authors: Anna M. Zhang, MD, Ahmed Elmoursi, MD, MPH, Daniel V. DiGiacomo, MD, MPH, Baijun Zhou, MHS, Megha Tandon, BA, Joseph S. Hong, BS, Nancy J. Yang, BS, Mei-Sing Ong, PhD, Anand S. Dighe, MD, PhD, Cristhian Berrios, MD, Mark C. Poznansky, MD, PhD, Anthony J. Iafrate, MD, PhD, Vivek Naranbhai, PhD, MB, ChB, Alejandro Balazs, PhD, Shiv Pillai, MBBS, PhD, Jocelyn R. Farmer, MD, PhD, Sara Barmettler, MD
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Journal of Allergy and Clinical Immunology: Global
Subjects:
Predominantly antibody deficiency
SARS-CoV-2
common variable immunodeficiency
anti-spike antibody
Omicron BA.5 variant
neutralization
Online Access:http://www.sciencedirect.com/science/article/pii/S2772829324000304

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