A Patient-Derived Xenograft Model of Dedifferentiated Endometrial Carcinoma: A Proof-of-Concept Study for the Identification of New Molecularly Informed Treatment Approaches

A Patient-Derived Xenograft Model of Dedifferentiated Endometrial Carcinoma: A Proof-of-Concept Study for the Identification of New Molecularly Informed Treatment Approaches

Conventional treatment of dedifferentiated endometrial carcinoma (DEC)–an uncommon and highly aggressive uterine malignancy–is beset by high failure rates. A line of research that holds promise to overcome these limitations is tailored treatments targeted on specific molecular alterations. However,...

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Bibliographic Details
Main Authors:	Chiao-Yun Lin, Ren-Chin Wu, Chen-Yang Huang, Chyong-Huey Lai, An-Shine Chao, Hsin-Pai Li, Chia-Lung Tsai, Elizabeth Joo-Wen Kuek, Cheng-Lung Hsu, Angel Chao
Format:	Article
Language:	English
Published:	MDPI AG 2021-11-01
Series:	Cancers
Subjects:	dedifferentiated endometrial carcinoma patient-derived xenograft models targeted treatment proof-of-concept lenvatinib palbociclib
Online Access:	https://www.mdpi.com/2072-6694/13/23/5962

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