A CLINICAL EXPERIENCE OF METHOTREXATE USE IN TREATMENT OF PATIENT WITH JUVENILE OLIGOARTHRITIS

This article presents clinical case of early manifestation of juvenile oligoarthritis with rapid contracture and destructive joint changes formation. Methotrexate was administered IM 15 mg/m2 once a week. After 3 months of treatment — acute inflammatory changes in the joint were relieved as well as...

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Bibliographic Details
Main Authors: K.B. Isaeva, E.I. Alexeeva, R.V. Denisova, T.V. Sleptsova, Т.М. Bzarova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2011-11-01
Series:Вопросы современной педиатрии
Subjects:
Online Access:https://vsp.spr-journal.ru/jour/article/view/800
Description
Summary:This article presents clinical case of early manifestation of juvenile oligoarthritis with rapid contracture and destructive joint changes formation. Methotrexate was administered IM 15 mg/m2 once a week. After 3 months of treatment — acute inflammatory changes in the joint were relieved as well as arthralgias, morning stiffness and there was a decrease in laboratory markers of the disease. After 6 months full motion range of the joint was achieved and contracture relieved. Remission is maintained for the last 12 months.Key words: children, juvenile arthritis, methotrexate. (Voprosy sovremennoi pediatrii — Current Pediatrics. — 2011; 10 (6): 191–197)
ISSN:1682-5527
1682-5535