High-fat diet exacerbates 1-Bromopropane-induced loss of dopaminergic neurons in the substantia nigra of mice through mitochondrial damage associated necroptotic pathway

High-fat diet exacerbates 1-Bromopropane-induced loss of dopaminergic neurons in the substantia nigra of mice through mitochondrial damage associated necroptotic pathway

In recent years, accumulating evidence supports that occupational exposure to solvents is associated with an increased incidence of Parkinson's disease (PD) among workers. The neurotoxic effects of 1-bromopropane (1-BP), a widely used new-type solvent, are well-established, yet data on its rela...

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Bibliographic Details
Main Authors: Mingxue Song, Yalong Qiang, Shuai Wang, Shan Shan, Liwen Zhang, Caipei Liu, Fuyong Song, Xiulan Zhao
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Ecotoxicology and Environmental Safety
Subjects:
1-Bromopropane
High-fat diet
Necroptosis
Neuroinflammation
Parkinson's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324003567

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