Research progress on the role of vitamin D supplementation in adjuvant therapy for COVID-19
The pandemic caused by coronavirus disease of 2019 （COVID-19） has brought severe challenges to public health all over the world. Vitamin D plays an important role in immune regulation and anti-respiratory virus infection as an immune enhancer. Several studies have demonstrated that vitamin D can reg...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of New Medicine
2022-12-01
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| Series: | Xin yixue |
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| Online Access: | https://www.xinyixue.cn/fileup/0253-9802/PDF/1672912137464-1711053268.pdf |
| Summary: | The pandemic caused by coronavirus disease of 2019 （COVID-19） has brought severe challenges to public health all over the world. Vitamin D plays an important role in immune regulation and anti-respiratory virus infection as an immune enhancer. Several studies have demonstrated that vitamin D can regulate the angiotensin-converting enzyme 2/angiotensin （1-7）/Mas receptor axis signaling pathway， inhibit the over-activation of renin-angiotensin system signal， fight against SARS-CoV-2 infection and suppress the production of inflammatory cytokine storm， thereby reducing the risk of pneumonia infection and improving acute respiratory distress syndrome， cardiogenic obstruction and thrombosis in COVID-19 patients. In this article， the mechanism of vitamin D in reducing the risk of SARS-CoV-2 infection and mitigating clinical symptoms was reviewed. It is hypothesized that vitamin D plays a critical role in the prevention or adjuvant therapy for novel coronavirus pneumonia and alleviating clinical manifestations in COVID-19 patients. |
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| ISSN: | 0253-9802 |