Research progress on the role of vitamin D supplementation in adjuvant therapy for COVID-19
The pandemic caused by coronavirus disease of 2019 （COVID-19） has brought severe challenges to public health all over the world. Vitamin D plays an important role in immune regulation and anti-respiratory virus infection as an immune enhancer. Several studies have demonstrated that vitamin D can reg...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of New Medicine
2022-12-01
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| Series: | Xin yixue |
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| Online Access: | https://www.xinyixue.cn/fileup/0253-9802/PDF/1672912137464-1711053268.pdf |
| _version_ | 1797960778458857472 |
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| author | Lei Yan, Zhan Shihuai, Shi Xiaohua, Wang Shuiliang, Zhao Meng, Zhang Shenghang |
| author_facet | Lei Yan, Zhan Shihuai, Shi Xiaohua, Wang Shuiliang, Zhao Meng, Zhang Shenghang |
| author_sort | Lei Yan, Zhan Shihuai, Shi Xiaohua, Wang Shuiliang, Zhao Meng, Zhang Shenghang |
| collection | DOAJ |
| description | The pandemic caused by coronavirus disease of 2019 （COVID-19） has brought severe challenges to public health all over the world. Vitamin D plays an important role in immune regulation and anti-respiratory virus infection as an immune enhancer. Several studies have demonstrated that vitamin D can regulate the angiotensin-converting enzyme 2/angiotensin （1-7）/Mas receptor axis signaling pathway， inhibit the over-activation of renin-angiotensin system signal， fight against SARS-CoV-2 infection and suppress the production of inflammatory cytokine storm， thereby reducing the risk of pneumonia infection and improving acute respiratory distress syndrome， cardiogenic obstruction and thrombosis in COVID-19 patients. In this article， the mechanism of vitamin D in reducing the risk of SARS-CoV-2 infection and mitigating clinical symptoms was reviewed. It is hypothesized that vitamin D plays a critical role in the prevention or adjuvant therapy for novel coronavirus pneumonia and alleviating clinical manifestations in COVID-19 patients. |
| first_indexed | 2024-04-11T00:49:34Z |
| format | Article |
| id | doaj.art-fb7e65f9752a428eb879b8558cb47550 |
| institution | Directory Open Access Journal |
| issn | 0253-9802 |
| language | zho |
| last_indexed | 2024-04-11T00:49:34Z |
| publishDate | 2022-12-01 |
| publisher | Editorial Office of Journal of New Medicine |
| record_format | Article |
| series | Xin yixue |
| spelling | doaj.art-fb7e65f9752a428eb879b8558cb475502023-01-05T09:53:13ZzhoEditorial Office of Journal of New MedicineXin yixue0253-98022022-12-01531287888110.3969/j.issn.0253-9802.2022.12.003Research progress on the role of vitamin D supplementation in adjuvant therapy for COVID-19Lei Yan, Zhan Shihuai, Shi Xiaohua, Wang Shuiliang, Zhao Meng, Zhang Shenghang0△Department of Clinical Laboratory， Fujian Key Laboratory of Aptamer Technology， the 900th Hospital of Joint Logistics Support Force， Fuzhou 350025， ChinaThe pandemic caused by coronavirus disease of 2019 （COVID-19） has brought severe challenges to public health all over the world. Vitamin D plays an important role in immune regulation and anti-respiratory virus infection as an immune enhancer. Several studies have demonstrated that vitamin D can regulate the angiotensin-converting enzyme 2/angiotensin （1-7）/Mas receptor axis signaling pathway， inhibit the over-activation of renin-angiotensin system signal， fight against SARS-CoV-2 infection and suppress the production of inflammatory cytokine storm， thereby reducing the risk of pneumonia infection and improving acute respiratory distress syndrome， cardiogenic obstruction and thrombosis in COVID-19 patients. In this article， the mechanism of vitamin D in reducing the risk of SARS-CoV-2 infection and mitigating clinical symptoms was reviewed. It is hypothesized that vitamin D plays a critical role in the prevention or adjuvant therapy for novel coronavirus pneumonia and alleviating clinical manifestations in COVID-19 patients.https://www.xinyixue.cn/fileup/0253-9802/PDF/1672912137464-1711053268.pdf|sars-cov-2|covid-19|vitamin d|cytokine storm|pneumonia |
| spellingShingle | Lei Yan, Zhan Shihuai, Shi Xiaohua, Wang Shuiliang, Zhao Meng, Zhang Shenghang Research progress on the role of vitamin D supplementation in adjuvant therapy for COVID-19 Xin yixue |sars-cov-2|covid-19|vitamin d|cytokine storm|pneumonia |
| title | Research progress on the role of vitamin D supplementation in adjuvant therapy for COVID-19 |
| title_full | Research progress on the role of vitamin D supplementation in adjuvant therapy for COVID-19 |
| title_fullStr | Research progress on the role of vitamin D supplementation in adjuvant therapy for COVID-19 |
| title_full_unstemmed | Research progress on the role of vitamin D supplementation in adjuvant therapy for COVID-19 |
| title_short | Research progress on the role of vitamin D supplementation in adjuvant therapy for COVID-19 |
| title_sort | research progress on the role of vitamin d supplementation in adjuvant therapy for covid 19 |
| topic | |sars-cov-2|covid-19|vitamin d|cytokine storm|pneumonia |
| url | https://www.xinyixue.cn/fileup/0253-9802/PDF/1672912137464-1711053268.pdf |
| work_keys_str_mv | AT leiyanzhanshihuaishixiaohuawangshuiliangzhaomengzhangshenghang researchprogressontheroleofvitamindsupplementationinadjuvanttherapyforcovid19 |