Zymosan attenuates melanoma growth progression, increases splenocyte proliferation and induces TLR-2/4 and TNF-α expression in mice

Zymosan attenuates melanoma growth progression, increases splenocyte proliferation and induces TLR-2/4 and TNF-α expression in mice

Abstract Background Melanoma is one of the most common types of skin malignancies. Since current therapies are suboptimal, considerable interest has focused on novel natural-based treatments. Toll-like receptors (TLRs) play an important role in evoking innate immunity against cancer cells. Zymosan,...

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Bibliographic Details
Main Authors: Mehdi Taghavi, Esmaeil Mortaz, Alireza Khosravi, Ghasem Vahedi, Gert Folkerts, Mohammad Varahram, Mehdi Kazempour-Dizaji, Johan Garssen, Ian M. Adcock
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Inflammation
Subjects:
TLR-2
TLR-4
TNF-α
Zymosan
Online Access:http://link.springer.com/article/10.1186/s12950-018-0182-y

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