Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review
This review describes the various innovative approaches implemented for naringin extraction as well as the recent developments in the field. Naringin was assessed in terms of its structure, chemical composition, and potential food sources. How naringin works pharmacologically was discussed, includin...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/15/5623 |
| _version_ | 1797586421518696448 |
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| author | VS Shilpa Rafeeya Shams Kshirod Kumar Dash Vinay Kumar Pandey Aamir Hussain Dar Shaikh Ayaz Mukarram Endre Harsányi Béla Kovács |
| author_facet | VS Shilpa Rafeeya Shams Kshirod Kumar Dash Vinay Kumar Pandey Aamir Hussain Dar Shaikh Ayaz Mukarram Endre Harsányi Béla Kovács |
| author_sort | VS Shilpa |
| collection | DOAJ |
| description | This review describes the various innovative approaches implemented for naringin extraction as well as the recent developments in the field. Naringin was assessed in terms of its structure, chemical composition, and potential food sources. How naringin works pharmacologically was discussed, including its potential as an anti-diabetic, anti-inflammatory, and hepatoprotective substance. Citrus flavonoids are crucial herbal additives that have a huge spectrum of organic activities. Naringin is a nutritional flavanone glycoside that has been shown to be effective in the treatment of a few chronic disorders associated with ageing. Citrus fruits contain a common flavone glycoside that has specific pharmacological and biological properties. Naringin, a flavone glycoside with a range of intriguing characteristics, is abundant in citrus fruits. Naringin has been shown to have a variety of biological, medicinal, and pharmacological effects. Naringin is hydrolyzed into rhamnose and prunin by the naringinase, which also possesses l-rhamnosidase activity. D-glucosidase subsequently catalyzes the hydrolysis of prunin into glucose and naringenin. Naringin is known for having anti-inflammatory, antioxidant, and tumor-fighting effects. Numerous test animals and cell lines have been used to correlate naringin exposure to asthma, hyperlipidemia, diabetes, cancer, hyperthyroidism, and osteoporosis. This study focused on the many documented actions of naringin in in-vitro and in-vivo experimental and preclinical investigations, as well as its prospective therapeutic advantages, utilizing the information that is presently accessible in the literature. In addition to its pharmacokinetic characteristics, naringin’s structure, distribution, different extraction methods, and potential use in the cosmetic, food, pharmaceutical, and animal feed sectors were discussed. |
| first_indexed | 2024-03-11T00:23:00Z |
| format | Article |
| id | doaj.art-fb81be2b5fbf4712a965aa3da1e2ce40 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T00:23:00Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-fb81be2b5fbf4712a965aa3da1e2ce402023-11-18T23:16:41ZengMDPI AGMolecules1420-30492023-07-012815562310.3390/molecules28155623Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A ReviewVS Shilpa0Rafeeya Shams1Kshirod Kumar Dash2Vinay Kumar Pandey3Aamir Hussain Dar4Shaikh Ayaz Mukarram5Endre Harsányi6Béla Kovács7Department of Food Technology & Nutrition, Lovely Professional University, Phagwara 144001, Punjab, IndiaDepartment of Food Technology & Nutrition, Lovely Professional University, Phagwara 144001, Punjab, IndiaDepartment of Food Processing Technology, Ghani Khan Choudhury Institute of Engineering and Technology Malda, Malda 732141, West Bengal, IndiaDepartment of Bioengineering, Integral University, Lucknow 226026, Uttar Pradesh, IndiaDepartment of Food Technology, Islamic University of Science and Technology, Awantipora 192122, Kashmir, IndiaFaculty of Agriculture, Food Science and Environmental Management Institute of Food Science, University of Debrecen, 4032 Debrecen, HungaryFaculty of Agriculture, Food Science and Environmental Management, Institute of Land Utilization, Engineering and Precision Technology, University of Debrecen, 4032 Debrecen, HungaryFaculty of Agriculture, Food Science and Environmental Management Institute of Food Science, University of Debrecen, 4032 Debrecen, HungaryThis review describes the various innovative approaches implemented for naringin extraction as well as the recent developments in the field. Naringin was assessed in terms of its structure, chemical composition, and potential food sources. How naringin works pharmacologically was discussed, including its potential as an anti-diabetic, anti-inflammatory, and hepatoprotective substance. Citrus flavonoids are crucial herbal additives that have a huge spectrum of organic activities. Naringin is a nutritional flavanone glycoside that has been shown to be effective in the treatment of a few chronic disorders associated with ageing. Citrus fruits contain a common flavone glycoside that has specific pharmacological and biological properties. Naringin, a flavone glycoside with a range of intriguing characteristics, is abundant in citrus fruits. Naringin has been shown to have a variety of biological, medicinal, and pharmacological effects. Naringin is hydrolyzed into rhamnose and prunin by the naringinase, which also possesses l-rhamnosidase activity. D-glucosidase subsequently catalyzes the hydrolysis of prunin into glucose and naringenin. Naringin is known for having anti-inflammatory, antioxidant, and tumor-fighting effects. Numerous test animals and cell lines have been used to correlate naringin exposure to asthma, hyperlipidemia, diabetes, cancer, hyperthyroidism, and osteoporosis. This study focused on the many documented actions of naringin in in-vitro and in-vivo experimental and preclinical investigations, as well as its prospective therapeutic advantages, utilizing the information that is presently accessible in the literature. In addition to its pharmacokinetic characteristics, naringin’s structure, distribution, different extraction methods, and potential use in the cosmetic, food, pharmaceutical, and animal feed sectors were discussed.https://www.mdpi.com/1420-3049/28/15/5623naringinflavonoidextractionbioactive potentialpharmaceutical |
| spellingShingle | VS Shilpa Rafeeya Shams Kshirod Kumar Dash Vinay Kumar Pandey Aamir Hussain Dar Shaikh Ayaz Mukarram Endre Harsányi Béla Kovács Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review Molecules naringin flavonoid extraction bioactive potential pharmaceutical |
| title | Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review |
| title_full | Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review |
| title_fullStr | Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review |
| title_full_unstemmed | Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review |
| title_short | Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review |
| title_sort | phytochemical properties extraction and pharmacological benefits of naringin a review |
| topic | naringin flavonoid extraction bioactive potential pharmaceutical |
| url | https://www.mdpi.com/1420-3049/28/15/5623 |
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