Age-related behavioral phenotype of an astrocytic monoamine oxidase-B transgenic mouse model of Parkinson's disease.

We have previously shown that increases in astrocytic monoamine oxidase-B (MAO-B) expression, mimicking that which occurs with aging and in neurodegenerative disease, in a doxycycline (dox)-inducible transgenic mouse model evokes neuropathological similarities to what is observed in the human parkin...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Christopher A Lieu, Shankar J Chinta, Anand Rane, Julie K Andersen
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Public Library of Science (PLoS) 2013-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC3542194?pdf=render