Optimal Interplay between Synaptic Strengths and Network Structure Enhances Activity Fluctuations and Information Propagation in Hierarchical Modular Networks
In network models of spiking neurons, the joint impact of network structure and synaptic parameters on activity propagation is still an open problem. Here, we use an information-theoretical approach to investigate activity propagation in spiking networks with a hierarchical modular topology. We obse...
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MDPI AG
2020-04-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/10/4/228 |
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| author | Rodrigo F. O. Pena Vinicius Lima Renan O. Shimoura João Paulo Novato Antonio C. Roque |
| author_facet | Rodrigo F. O. Pena Vinicius Lima Renan O. Shimoura João Paulo Novato Antonio C. Roque |
| author_sort | Rodrigo F. O. Pena |
| collection | DOAJ |
| description | In network models of spiking neurons, the joint impact of network structure and synaptic parameters on activity propagation is still an open problem. Here, we use an information-theoretical approach to investigate activity propagation in spiking networks with a hierarchical modular topology. We observe that optimized pairwise information propagation emerges due to the increase of either (i) the global synaptic strength parameter or (ii) the number of modules in the network, while the network size remains constant. At the population level, information propagation of activity among adjacent modules is enhanced as the number of modules increases until a maximum value is reached and then decreases, showing that there is an optimal interplay between synaptic strength and modularity for population information flow. This is in contrast to information propagation evaluated among pairs of neurons, which attains maximum value at the maximum values of these two parameter ranges. By examining the network behavior under the increase of synaptic strength and the number of modules, we find that these increases are associated with two different effects: (i) the increase of autocorrelations among individual neurons and (ii) the increase of cross-correlations among pairs of neurons. The second effect is associated with better information propagation in the network. Our results suggest roles that link topological features and synaptic strength levels to the transmission of information in cortical networks. |
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| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T20:32:32Z |
| publishDate | 2020-04-01 |
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| spelling | doaj.art-fb87f38e2b4840b6b0634bcbcdf9136f2023-11-19T21:19:17ZengMDPI AGBrain Sciences2076-34252020-04-0110422810.3390/brainsci10040228Optimal Interplay between Synaptic Strengths and Network Structure Enhances Activity Fluctuations and Information Propagation in Hierarchical Modular NetworksRodrigo F. O. Pena0Vinicius Lima1Renan O. Shimoura2João Paulo Novato3Antonio C. Roque4Department of Physics, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, CEP 14040-901 Ribeirão Preto, SP, BrazilDepartment of Physics, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, CEP 14040-901 Ribeirão Preto, SP, BrazilDepartment of Physics, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, CEP 14040-901 Ribeirão Preto, SP, BrazilDepartment of Physics, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, CEP 14040-901 Ribeirão Preto, SP, BrazilDepartment of Physics, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, CEP 14040-901 Ribeirão Preto, SP, BrazilIn network models of spiking neurons, the joint impact of network structure and synaptic parameters on activity propagation is still an open problem. Here, we use an information-theoretical approach to investigate activity propagation in spiking networks with a hierarchical modular topology. We observe that optimized pairwise information propagation emerges due to the increase of either (i) the global synaptic strength parameter or (ii) the number of modules in the network, while the network size remains constant. At the population level, information propagation of activity among adjacent modules is enhanced as the number of modules increases until a maximum value is reached and then decreases, showing that there is an optimal interplay between synaptic strength and modularity for population information flow. This is in contrast to information propagation evaluated among pairs of neurons, which attains maximum value at the maximum values of these two parameter ranges. By examining the network behavior under the increase of synaptic strength and the number of modules, we find that these increases are associated with two different effects: (i) the increase of autocorrelations among individual neurons and (ii) the increase of cross-correlations among pairs of neurons. The second effect is associated with better information propagation in the network. Our results suggest roles that link topological features and synaptic strength levels to the transmission of information in cortical networks.https://www.mdpi.com/2076-3425/10/4/228hierarchical modular networkscortical network modelsneural information processingdelayed transfer entropyneural activity fluctuations |
| spellingShingle | Rodrigo F. O. Pena Vinicius Lima Renan O. Shimoura João Paulo Novato Antonio C. Roque Optimal Interplay between Synaptic Strengths and Network Structure Enhances Activity Fluctuations and Information Propagation in Hierarchical Modular Networks Brain Sciences hierarchical modular networks cortical network models neural information processing delayed transfer entropy neural activity fluctuations |
| title | Optimal Interplay between Synaptic Strengths and Network Structure Enhances Activity Fluctuations and Information Propagation in Hierarchical Modular Networks |
| title_full | Optimal Interplay between Synaptic Strengths and Network Structure Enhances Activity Fluctuations and Information Propagation in Hierarchical Modular Networks |
| title_fullStr | Optimal Interplay between Synaptic Strengths and Network Structure Enhances Activity Fluctuations and Information Propagation in Hierarchical Modular Networks |
| title_full_unstemmed | Optimal Interplay between Synaptic Strengths and Network Structure Enhances Activity Fluctuations and Information Propagation in Hierarchical Modular Networks |
| title_short | Optimal Interplay between Synaptic Strengths and Network Structure Enhances Activity Fluctuations and Information Propagation in Hierarchical Modular Networks |
| title_sort | optimal interplay between synaptic strengths and network structure enhances activity fluctuations and information propagation in hierarchical modular networks |
| topic | hierarchical modular networks cortical network models neural information processing delayed transfer entropy neural activity fluctuations |
| url | https://www.mdpi.com/2076-3425/10/4/228 |
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