New roles of N6-methyladenosine methylation system regulating the occurrence of non-alcoholic fatty liver disease with N6-methyladenosine-modified MYC

New roles of N6-methyladenosine methylation system regulating the occurrence of non-alcoholic fatty liver disease with N6-methyladenosine-modified MYC

Non-alcoholic fatty liver disease (NAFLD) has become a major chronic disease in contemporary society, affected by N6-methyladenosine (m6A) RNA methylation, one of the most common RNA modifications. Compared with healthy control, m6A RNA methyltransferase 3 (METTL3) and METTL14 increased, while Wilms...

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Bibliographic Details
Main Authors: Wenli Cheng, Min Li, Luyun Zhang, Cheng Zhou, Susu Yu, Xinyue Peng, Wenji Zhang, Wenjuan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
non-alcoholic fatty liver disease (NAFLD)
non-alcoholic steatohepatitis (NASH)
N6-methyladenosine (m6A)
RNA methylation
MYC
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.973116/full

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