Liproxstatin-1 Alleviated Ischemia/Reperfusion-Induced Acute Kidney Injury via Inhibiting Ferroptosis

Liproxstatin-1 Alleviated Ischemia/Reperfusion-Induced Acute Kidney Injury via Inhibiting Ferroptosis

Ferroptosis, as a novel regulable cell death, is characterized by iron overload, glutathione depletion, and an accumulation of lipid peroxides. Recently, it has been discovered that ferroptosis is involved in ischemia/reperfusion (I/R)-induced acute kidney injury (AKI) and plays a crucial role in re...

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Bibliographic Details
Main Authors: Zhiyuan Shi, Yifan Du, Jianzhong Zheng, Wenbin Tang, Qing Liang, Zeyuan Zheng, Bin Liu, Huimin Sun, Kejia Wang, Chen Shao
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Antioxidants
Subjects:
liproxstatin-1
ischemia/reperfusion
acute kidney injury
ferroptosis
EGR1
Online Access:https://www.mdpi.com/2076-3921/13/2/182

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