Auditory white noise exposure results in intrinsic cortical excitability changes
Summary: Cortical excitability is commonly measured by applying magnetic stimulation in combination with measuring behavioral response. This measure has, however, some shortcomings including spatial limitation to the primary motor cortex and not accounting for intrinsic excitability fluctuations. He...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-08-01
|
| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004223014645 |
| _version_ | 1827877554708545536 |
|---|---|
| author | Anna-Lisa Schuler Diandra Brkić Giulio Ferrazzi Giorgio Arcara Daniele Marinazzo Giovanni Pellegrino |
| author_facet | Anna-Lisa Schuler Diandra Brkić Giulio Ferrazzi Giorgio Arcara Daniele Marinazzo Giovanni Pellegrino |
| author_sort | Anna-Lisa Schuler |
| collection | DOAJ |
| description | Summary: Cortical excitability is commonly measured by applying magnetic stimulation in combination with measuring behavioral response. This measure has, however, some shortcomings including spatial limitation to the primary motor cortex and not accounting for intrinsic excitability fluctuations. Here, we use a measure for intrinsic excitability based on phase synchronization previously validated for epilepsy. We apply this measure in 30 healthy participants’ magnetoencephalography (MEG) recordings during the exposure of auditory white noise, a stimulus that has been suggested to modify cortical excitability. Using cortical parcellation of the MEG source data, we could find a specific pattern of increased and decreased excitability while participants are exposed to white noise vs. silence. Specifically, excitability during white noise exposure decreases in the frontal lobe and increases in the temporal lobe. This study thus adds to the understanding of cortical excitability changes due to specific environmental stimuli as well as the spatial extent of these effects. |
| first_indexed | 2024-03-12T17:39:16Z |
| format | Article |
| id | doaj.art-fb9030ed4b744603b87c607c8a84374a |
| institution | Directory Open Access Journal |
| issn | 2589-0042 |
| language | English |
| last_indexed | 2024-03-12T17:39:16Z |
| publishDate | 2023-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj.art-fb9030ed4b744603b87c607c8a84374a2023-08-04T05:51:02ZengElsevieriScience2589-00422023-08-01268107387Auditory white noise exposure results in intrinsic cortical excitability changesAnna-Lisa Schuler0Diandra Brkić1Giulio Ferrazzi2Giorgio Arcara3Daniele Marinazzo4Giovanni Pellegrino5IRCCS San Camillo Hospital, Venice, Italy; Lise Meitner Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Corresponding authorIRCCS San Camillo Hospital, Venice, ItalyPhilips Healthcare, Milan, ItalyIRCCS San Camillo Hospital, Venice, ItalyDepartment of Data Analysis, Faculty of Psychology and Educational Sciences, Ghent University, Ghent, BelgiumEpilepsy Program, Schulich School of Medicine and Dentistry, Western University, London, ON, CanadaSummary: Cortical excitability is commonly measured by applying magnetic stimulation in combination with measuring behavioral response. This measure has, however, some shortcomings including spatial limitation to the primary motor cortex and not accounting for intrinsic excitability fluctuations. Here, we use a measure for intrinsic excitability based on phase synchronization previously validated for epilepsy. We apply this measure in 30 healthy participants’ magnetoencephalography (MEG) recordings during the exposure of auditory white noise, a stimulus that has been suggested to modify cortical excitability. Using cortical parcellation of the MEG source data, we could find a specific pattern of increased and decreased excitability while participants are exposed to white noise vs. silence. Specifically, excitability during white noise exposure decreases in the frontal lobe and increases in the temporal lobe. This study thus adds to the understanding of cortical excitability changes due to specific environmental stimuli as well as the spatial extent of these effects.http://www.sciencedirect.com/science/article/pii/S2589004223014645NeuroscienceSensory neuroscience |
| spellingShingle | Anna-Lisa Schuler Diandra Brkić Giulio Ferrazzi Giorgio Arcara Daniele Marinazzo Giovanni Pellegrino Auditory white noise exposure results in intrinsic cortical excitability changes iScience Neuroscience Sensory neuroscience |
| title | Auditory white noise exposure results in intrinsic cortical excitability changes |
| title_full | Auditory white noise exposure results in intrinsic cortical excitability changes |
| title_fullStr | Auditory white noise exposure results in intrinsic cortical excitability changes |
| title_full_unstemmed | Auditory white noise exposure results in intrinsic cortical excitability changes |
| title_short | Auditory white noise exposure results in intrinsic cortical excitability changes |
| title_sort | auditory white noise exposure results in intrinsic cortical excitability changes |
| topic | Neuroscience Sensory neuroscience |
| url | http://www.sciencedirect.com/science/article/pii/S2589004223014645 |
| work_keys_str_mv | AT annalisaschuler auditorywhitenoiseexposureresultsinintrinsiccorticalexcitabilitychanges AT diandrabrkic auditorywhitenoiseexposureresultsinintrinsiccorticalexcitabilitychanges AT giulioferrazzi auditorywhitenoiseexposureresultsinintrinsiccorticalexcitabilitychanges AT giorgioarcara auditorywhitenoiseexposureresultsinintrinsiccorticalexcitabilitychanges AT danielemarinazzo auditorywhitenoiseexposureresultsinintrinsiccorticalexcitabilitychanges AT giovannipellegrino auditorywhitenoiseexposureresultsinintrinsiccorticalexcitabilitychanges |