Hypoxic State of Cells and Immunosenescence: A Focus on the Role of the HIF Signaling Pathway

Hypoxic State of Cells and Immunosenescence: A Focus on the Role of the HIF Signaling Pathway

Hypoxia activates hypoxia-related signaling pathways controlled by hypoxia-inducible factors (HIFs). HIFs represent a quick and effective detection system involved in the cellular response to insufficient oxygen concentration. Activation of HIF signaling pathways is involved in improving the oxygen...

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Bibliographic Details
Main Authors: Dario Troise, Barbara Infante, Silvia Mercuri, Giuseppe Stefano Netti, Elena Ranieri, Loreto Gesualdo, Giovanni Stallone, Paola Pontrelli
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomedicines
Subjects:
hypoxia-inducible factors
cellular aging
cellular energy
immunosenescence
Online Access:https://www.mdpi.com/2227-9059/11/8/2163

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