Covalent Organic Framework/Polyacrylonitrile Electrospun Nanofiber for Dispersive Solid-Phase Extraction of Trace Quinolones in Food Samples
The extraction of quinolone antibiotics (QAs) is crucial for the environment and human health. In this work, polyacrylonitrile (PAN)/covalent organic framework TpPa–1 nanofiber was prepared by an electrospinning technique and used as an adsorbent for dispersive solid-phase extraction (dSPE) of five...
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MDPI AG
2022-07-01
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| Series: | Nanomaterials |
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| author | Jinghui Zhou An Chen Hongying Guo Yijun Li Xiwen He Langxing Chen Yukui Zhang |
| author_facet | Jinghui Zhou An Chen Hongying Guo Yijun Li Xiwen He Langxing Chen Yukui Zhang |
| author_sort | Jinghui Zhou |
| collection | DOAJ |
| description | The extraction of quinolone antibiotics (QAs) is crucial for the environment and human health. In this work, polyacrylonitrile (PAN)/covalent organic framework TpPa–1 nanofiber was prepared by an electrospinning technique and used as an adsorbent for dispersive solid-phase extraction (dSPE) of five QAs in the honey and pork. The morphology and structure of the adsorbent were characterized, and the extraction and desorption conditions for the targeted analytes were optimized. Under the optimal conditions, a sensitive method was developed by using PAN/TpPa–1 nanofiber as an adsorbent coupled with high-performance liquid chromatography (HPLC) for five QAs detection. It offered good linearity in the ranges of 0.5–200 ng·mL<sup>−1</sup> for pefloxacin, enrofloxacin, and orbifloxacin, and of 1–200 ng·mL<sup>−1</sup> for norfloxacin and sarafloxacin with correlation coefficients above 0.9946. The limits of detection (S/N = 3) of five QAs ranged from 0.03 to 0.133 ng·mL<sup>−1</sup>. The intra-day and inter-day relative standard deviations of the five QAs with the spiked concentration of 50 ng·mL<sup>−1</sup> were 2.8–4.0 and 3.0–8.8, respectively. The recoveries of five QAs in the honey and pork samples were 81.6–119.7%, which proved that the proposed method has great potential for the efficient extraction and determination of QAs in complex samples. |
| first_indexed | 2024-03-09T06:06:52Z |
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| language | English |
| last_indexed | 2024-03-09T06:06:52Z |
| publishDate | 2022-07-01 |
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| series | Nanomaterials |
| spelling | doaj.art-fb9c7bbb86e84b728329d52e9c723fc52023-12-03T12:03:42ZengMDPI AGNanomaterials2079-49912022-07-011214248210.3390/nano12142482Covalent Organic Framework/Polyacrylonitrile Electrospun Nanofiber for Dispersive Solid-Phase Extraction of Trace Quinolones in Food SamplesJinghui Zhou0An Chen1Hongying Guo2Yijun Li3Xiwen He4Langxing Chen5Yukui Zhang6College of Chemistry, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin 300071, ChinaCollege of Chemistry, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin 300071, ChinaCollege of Chemistry, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin 300071, ChinaCollege of Chemistry, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin 300071, ChinaCollege of Chemistry, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin 300071, ChinaCollege of Chemistry, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin 300071, ChinaCollege of Chemistry, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin 300071, ChinaThe extraction of quinolone antibiotics (QAs) is crucial for the environment and human health. In this work, polyacrylonitrile (PAN)/covalent organic framework TpPa–1 nanofiber was prepared by an electrospinning technique and used as an adsorbent for dispersive solid-phase extraction (dSPE) of five QAs in the honey and pork. The morphology and structure of the adsorbent were characterized, and the extraction and desorption conditions for the targeted analytes were optimized. Under the optimal conditions, a sensitive method was developed by using PAN/TpPa–1 nanofiber as an adsorbent coupled with high-performance liquid chromatography (HPLC) for five QAs detection. It offered good linearity in the ranges of 0.5–200 ng·mL<sup>−1</sup> for pefloxacin, enrofloxacin, and orbifloxacin, and of 1–200 ng·mL<sup>−1</sup> for norfloxacin and sarafloxacin with correlation coefficients above 0.9946. The limits of detection (S/N = 3) of five QAs ranged from 0.03 to 0.133 ng·mL<sup>−1</sup>. The intra-day and inter-day relative standard deviations of the five QAs with the spiked concentration of 50 ng·mL<sup>−1</sup> were 2.8–4.0 and 3.0–8.8, respectively. The recoveries of five QAs in the honey and pork samples were 81.6–119.7%, which proved that the proposed method has great potential for the efficient extraction and determination of QAs in complex samples.https://www.mdpi.com/2079-4991/12/14/2482electrospun nanofibercovalent organic frameworksdispersive solid-phase extractionquinolonesfood samples |
| spellingShingle | Jinghui Zhou An Chen Hongying Guo Yijun Li Xiwen He Langxing Chen Yukui Zhang Covalent Organic Framework/Polyacrylonitrile Electrospun Nanofiber for Dispersive Solid-Phase Extraction of Trace Quinolones in Food Samples Nanomaterials electrospun nanofiber covalent organic frameworks dispersive solid-phase extraction quinolones food samples |
| title | Covalent Organic Framework/Polyacrylonitrile Electrospun Nanofiber for Dispersive Solid-Phase Extraction of Trace Quinolones in Food Samples |
| title_full | Covalent Organic Framework/Polyacrylonitrile Electrospun Nanofiber for Dispersive Solid-Phase Extraction of Trace Quinolones in Food Samples |
| title_fullStr | Covalent Organic Framework/Polyacrylonitrile Electrospun Nanofiber for Dispersive Solid-Phase Extraction of Trace Quinolones in Food Samples |
| title_full_unstemmed | Covalent Organic Framework/Polyacrylonitrile Electrospun Nanofiber for Dispersive Solid-Phase Extraction of Trace Quinolones in Food Samples |
| title_short | Covalent Organic Framework/Polyacrylonitrile Electrospun Nanofiber for Dispersive Solid-Phase Extraction of Trace Quinolones in Food Samples |
| title_sort | covalent organic framework polyacrylonitrile electrospun nanofiber for dispersive solid phase extraction of trace quinolones in food samples |
| topic | electrospun nanofiber covalent organic frameworks dispersive solid-phase extraction quinolones food samples |
| url | https://www.mdpi.com/2079-4991/12/14/2482 |
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