The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs
Positive allosteric modulators for free fatty acid receptor 2 (FFAR2/GPR43), that affect receptor function through binding to two distinct allosteric binding sites, were used to determine the correlation between the responses induced in neutrophils by two distinct activation modes; FFAR2 was activat...
Main Authors: | Simon Lind, Kenneth L. Granberg, Huamei Forsman, Claes Dahlgren |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079109/?tool=EBI |
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