Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes

Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes

The molecular mechanisms explaining racial disparity in breast cancer mortality are not completely elucidated. Here, the authors show that an African-associated SNP in American breast cancer patients, leads to higher levels of microRNA miR-1304-3p which promotes cancer by increasing lipids availabil...

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Bibliographic Details
Main Authors: Dan Zhao, Kerui Wu, Sambad Sharma, Fei Xing, Shih-Ying Wu, Abhishek Tyagi, Ravindra Deshpande, Ravi Singh, Martin Wabitsch, Yin-Yuan Mo, Kounosuke Watabe
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35305-2

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