Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions.

Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions.

Influenza A viruses (IAV) are commonly used to infect animal cell cultures for research purposes and vaccine production. Their replication is influenced strongly by the multiplicity of infection (MOI), which ranges over several orders of magnitude depending on the respective application. So far, mat...

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Bibliographic Details
Main Authors: Daniel Rüdiger, Sascha Young Kupke, Tanja Laske, Pawel Zmora, Udo Reichl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006819

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