Exogenous carbon monoxide promotes GPX4-dependent ferroptosis through ROS/GSK3β axis in non-small cell lung cancer

Exogenous carbon monoxide promotes GPX4-dependent ferroptosis through ROS/GSK3β axis in non-small cell lung cancer

Abstract The gas therapy is drawing increasing attention in the treatment of many diseases including cancer. As one of gas signaling molecules, carbon monoxide (CO) has been proved to exert anti-cancer effects via triggering multiple cell death types, such as autophagy, apoptosis and necrosis. Here,...

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Bibliographic Details
Main Authors: Wei Cao, Mingyu Sun, K. N. Yu, Lele Zhao, Yue Feng, Chunhua Tan, Miaomiao Yang, Ying Wang, Fengqin Zhu, Lianjun Chen, Lili Nie, Ye Zhao, Guodong Chen, Wei Han
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01743-0

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