Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection
Chromatin dynamics is thought to play an important role in the maintenance of telomeres, yet how has remained poorly understood. Here the authors locally enrich heterochromatin protein 1α (HP1α) at human telomeres to provide insights into the crosstalk between epigenetic regulations and structural d...
Main Authors: | Tracy T. Chow, Xiaoyu Shi, Jen-Hsuan Wei, Juan Guan, Guido Stadler, Bo Huang, Elizabeth H. Blackburn |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05840-y |
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